An 8-year single-centre experience of patients with subclinical rheumatic carditis

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dc.authoridİrdem, Ahmet / 0000-0002-2565-5674
dc.contributor.authorİrdem, Ahmet
dc.contributor.authorErgin, Selma Oktay
dc.contributor.authorKaçar, Alper
dc.contributor.authorDağdeviren, Fatma Ece
dc.date.accessioned2025-01-27T20:34:56Z
dc.date.available2025-01-27T20:34:56Z
dc.date.issued2024
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Transthoracic echocardiography is the gold standard method for screening and confirmation of acute rheumatic fever and subclinical rheumatic heart disease. Secondary antibiotic prophylaxis that is regularly employed in subclinical rheumatic heart disease may help to reverse mild rheumatic carditis lesions, delay the progression of the disease, reduce morbidity and mortality, and improve patients’ quality of life. Materials and Methods: We retrospectively evaluated the outcomes of 180 patients with subclinical rheumatic heart disease who were followed up for a mean of 4.92 ± 2.0 (3.5–6.5) years. Results: Between 1 March 2015 and 31 December 2023, 180 patients diagnosed with subclinical rheumatic heart disease with a mean follow-up of 4.92 ± 2.0 (3.5–6.5) years were included in the study. Of the patients, 50.6% were male, 49.4% were female, mean age at diagnosis was 11.74 ± 3.18 (9.68–13.65) years, and mean follow-up period was 4.92 ± 2.0 (3.5–6.5) years. Further, 87.2 % of the patients had mitral valve regurgitation, 38.3% had aortic valve regurgitation, and 27.2% had both valve (aortic and mitral valve) regurgitation. Moreover, Sydenham chorea was also diagnosed in 7.8% the patients. Of the patients, 90% had mild rheumatic heart disease, 7.8% had moderate rheumatic heart disease, and 2.2% had severe rheumatic heart disease. After the diagnosis of rheumatic heart disease, 76.7% patients received regular and 23.3% irregular secondary benzathine penicillin G prophylaxis. Conclusion: We believe that echocardiography demonstrates its efficacy and safety profile in reducing the risk of rheumatic heart disease in patients diagnosed with subclinical rheumatic carditis and complying with regular secondary antibiotic prophylaxis.
dc.identifier.doi10.1017/S1047951124026453
dc.identifier.issn1047-9511
dc.identifier.issn1467-1107
dc.identifier.pmid39358846
dc.identifier.scopus2-s2.0-85206262406
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1017/S1047951124026453
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23519
dc.identifier.wosWOS:001324405300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge Univ Press
dc.relation.ispartofCardiology in The Young
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectchildren
dc.subjectsecondary prophylaxis
dc.subjectsubclinic rheumatic carditis
dc.titleAn 8-year single-centre experience of patients with subclinical rheumatic carditis
dc.typeArticle

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