Voltammetric Determination of Favipiravir Used as an Antiviral Drug for the Treatment of Covid-19 at Pencil Graphite Electrode
Yükleniyor...
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
John Wiley and Sons Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
This work describes the sensitive voltammetric determination of favipiravir (FAV) based on its reduction for the first time with a low-cost and disposable pencil graphite electrode (PGE). In addition, the determination of FAV was also performed based on its oxidation. Differential pulse (DP) voltammograms recorded in 0.5 M H2SO4 for the reduction of FAV show that peak currents increase linearly in the range of 1.0 to 600.0 μM with a limit of detection of 0.35 μM. The acceptable recovery values (98.9–106.0 %) obtained from a pharmaceutical tablet, real human urine, and artificial blood serum samples spiked with FAV confirm the high accuracy of the proposed method.
Açıklama
Anahtar Kelimeler
COVID-19, Differential Pulse Voltammetry, Favipiravir, Pencil graphite electrode
Kaynak
Electroanalysis
WoS Q Değeri
Q2
Scopus Q Değeri
Cilt
35
Sayı
4
Künye
Erşan, T., Dilgin, D. G., Kumrulu, E., Kumrulu, U., & Dilgin, Y. (2023). Voltammetric Determination of Favipiravir Used as an Antiviral Drug for the Treatment of Covid‐19 at Pencil Graphite Electrode. Electroanalysis, 35(4). https://doi.org/10.1002/elan.202200295
