The Frequency of Pancreatic Enzyme Elevations and Effect on Disease Severity in COVID-19
| dc.contributor.author | Çeviker, Sevil Alkan | |
| dc.contributor.author | Gökçe, Oruç Numan | |
| dc.contributor.author | Çinpolat, Havva Yasemin | |
| dc.date.accessioned | 2025-01-27T19:32:57Z | |
| dc.date.available | 2025-01-27T19:32:57Z | |
| dc.date.issued | 2023 | |
| dc.department | Çanakkale Onsekiz Mart Üniversitesi | |
| dc.description.abstract | Aim: In this study, we aimed to evaluate the frequency of pancreatic enzyme elevations in COVID-19-infected patients and to examine the effect on disease severity. Material and Methods: A total of 1249 patients who hospitalized with COVID-19 infection were included. The frequency of pancreatic enzyme elevations and the effect on disease severity in patients infected with COVID-19 were investigated. Results: The pancreatic enzyme elevations (amylase/lipase or both) were detected in 32 of 1249 patients (incidence 2.96%). 32 cases with a mean age of 64.97±5.63 years were included in this study. 30 (93.75%) of the cases were men’s gender. 31 (96.87%) of them had elevated amylase levels, 26 (81.25%) had elevated lipase levels and 25 (78.12%) of them had elevated both amylase and lipase levels. Only 10 (31.25%) of them tested radiological for acute pancreatitis (AP) and there was no radiological finding compatible with AP in any of the limited numbers of abdominal computerized tomography scans performed. 18 (56.25%) of the patients were transferred to the intensive care unit due to clinical worsening and mortality developed in 13 (40.62%) patients. The mean age of the deceased cases was 66.4±6.6 years and there was no statistically significant difference between deceased and survived COVID-19 patients (>0.05). Conclusion: The median lymphocyte count was lower, and the median AST, ALT, and lipase levels were higher in the deceased group. Perhaps close clinical follow-up of patients with pathological findings in these values and radiological imaging, if necessary, may be beneficial in the method of the disease. Keywords: COVID-19; disease severity; pancreatic enzyme elevations. | |
| dc.identifier.doi | 10.33631/sabd.1199161 | |
| dc.identifier.endpage | 215 | |
| dc.identifier.issn | 2792-0542 | |
| dc.identifier.issue | 2 | |
| dc.identifier.startpage | 209 | |
| dc.identifier.trdizinid | 1171173 | |
| dc.identifier.uri | https://doi.org/10.33631/sabd.1199161 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/tr/yayin/detay/1171173 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12428/16525 | |
| dc.identifier.volume | 13 | |
| dc.indekslendigikaynak | TR-Dizin | |
| dc.language.iso | en | |
| dc.relation.ispartof | Sağlık bilimlerinde değer (Online) | |
| dc.relation.publicationcategory | Other | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.snmz | KA_TRD_20250125 | |
| dc.subject | Tıbbi Araştırmalar Deneysel | |
| dc.subject | Genel ve Dahili Tıp | |
| dc.subject | Patoloji | |
| dc.title | The Frequency of Pancreatic Enzyme Elevations and Effect on Disease Severity in COVID-19 | |
| dc.type | Other |
