Electrochemical Determination of Phenazopyridine Hydrocloride using Poly(p-Aminobenzene Sulfonic Acid) Film Modified Glassy Carbon Electrode

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dc.authoridSaglikoglu, Gulsen/0000-0002-3407-9787
dc.authoridYilmaz, Selehattin/0000-0003-4607-3523
dc.contributor.authorDemirtas, Cigdem
dc.contributor.authorYilmaz, Selehattin
dc.contributor.authorSaglikoglu, Gulsen
dc.contributor.authorSadikoglu, Murat
dc.date.accessioned2025-01-27T20:43:35Z
dc.date.available2025-01-27T20:43:35Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPhenazopyridine hydrochloride is an antiviral effective drug active compound. A glassy carbon electrode (GCE) was modified with an electropolymerized film of p-aminobenzene sulfonic acid (p-ABSA) in phosphate buffer solution (PBS). The electrochemical properties of the polymer film were studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The polymer film-modified electrode was used to electrochemically detect phenazopyridine hydrochloride. Polymer film showed excellent electrocatalytic activity for the reduction of phenazopyridine hydrochloride. The catodic peak potential value of the phenazopyridine hydrochloride at the poly(p-ABSA) modified glassy carbon electrode was -334 mV obtained by DPV. A linear calibration curve for DPV analysis was constructed in the phenazopyridine hydrochloride concentration range 6x10(-6)-1x10(-5) mol L-1. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 2.1x10(-7) and 7x10(-7) mol L-1 respectively. The proposed method exhibits good recovery and reproducibility. The mechanisms of electropolymerization of p-ABSA are also suggested.
dc.identifier.endpage1892
dc.identifier.issn1452-3981
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84921656453
dc.identifier.scopusqualityQ3
dc.identifier.startpage1883
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24280
dc.identifier.volume10
dc.identifier.wosWOS:000348365800067
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherEsg
dc.relation.ispartofInternational Journal of Electrochemical Science
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectp-Aminobenzene sulfonic acid
dc.subjectModified glassy carbon electrode
dc.subjectElectropolymerization
dc.subjectElectrocatalytic reduction
dc.subjectDetermination of phenazopyridine hydrochloride
dc.subjectVoltammetry
dc.titleElectrochemical Determination of Phenazopyridine Hydrocloride using Poly(p-Aminobenzene Sulfonic Acid) Film Modified Glassy Carbon Electrode
dc.typeArticle

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