Isolates and antibiotic sensitivity of eighty culture-proven endophthalmitis cases from Istanbul

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dc.contributor.authorEser, Ilker
dc.contributor.authorKapran, Ziya
dc.contributor.authorAltan, Tugrul
dc.contributor.authorKaratas, Meltem Ozel
dc.contributor.authorAydin, Derya
dc.contributor.authorOkaygun, Eda
dc.contributor.authorYilmaz, Omer Faruk
dc.date.accessioned2025-01-27T21:05:58Z
dc.date.available2025-01-27T21:05:58Z
dc.date.issued2008
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description21st Congress of the Turkish-Society-of-Antimicrobial-Chemotherapy -- JUN, 2006 -- Antalya, TURKEY
dc.description.abstractPurpose: To investigate the spectrum of organisms causing endophthalmitis and their sensitivity to commonly used antimicrobial agents. Methods: Medical records of 80 consecutive patients treated at Beyoglu Eye Hospital for endophthalmitis from January 2001 to April 2006 were reviewed. Specimens were obtained from either the vitreous (93%, 81/87) or anterior chamber (7%, 6/87) during pars plana vitrectomy or vitreous tap, and were inoculated into blood culture bottles. A Kirby-Bauer disk diffusion test was performed to determine antibiotic susceptibility. The outcome measures included isolates identified and antibiotic sensitivity of the specimens. Results: Fifty-six of 87 (64.4%) isolates were Gram-positive organisms, 29 (33.3%) were Gram-negative organisms, and 2 (2.3%) were fungi. The most common organism group identified was coagulase-negative staphylococci in 26.4% (23/87). While vancomycin was active against all Gram-positive isolates tested (100%), ceftazidime had the highest susceptibility rate (100%) for Gram-negative organisms isolated. Conclusions: Although coagulase-negative micrococci predominated in this series, a high isolation rate for Gram-negative organisms was obtained. High susceptibility rates for ofloxacin make it an alternative to ceftazidime and vancomycin in both Gram-negative- and Gram-positive-derived endophthalmitis, respectively. Studies with larger series and additional antibiotics are needed to confirm these findings. Copyright (C) 2008 S. Karger AG, Basel.
dc.description.sponsorshipTurkish Soc Antimicrobial Chemotherapy
dc.identifier.doi10.1159/000126077
dc.identifier.endpage160
dc.identifier.issn0030-3755
dc.identifier.issn1423-0267
dc.identifier.issue3
dc.identifier.pmid18497523
dc.identifier.scopus2-s2.0-44349104642
dc.identifier.scopusqualityQ1
dc.identifier.startpage157
dc.identifier.urihttps://doi.org/10.1159/000126077
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27853
dc.identifier.volume222
dc.identifier.wosWOS:000256353500004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofOphthalmologica
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectantibiotic susceptibility
dc.subjectendophthalmitis
dc.subjectStaphylococcus
dc.subjectvitrectomy
dc.titleIsolates and antibiotic sensitivity of eighty culture-proven endophthalmitis cases from Istanbul
dc.typeConference Object

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