Hypochlorous Acid: A Novel Agent Against Echinococcus granulosus Protoscoleces

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dc.authoridGökçe, Oruç Numan / 0000-0002-9678-7818
dc.authoridÇetin, Kenan / 0000-0002-8616-9784
dc.authoridAlkan, Sevil / 0000-0003-1944-2477
dc.authoridTaş, Şükrü / 0000-0001-6178-7546
dc.contributor.authorGökçe, Oruç Numan
dc.contributor.authorÇetin, Kenan
dc.contributor.authorAlkan, Sevil
dc.contributor.authorTaş, Şükrü
dc.contributor.authorDinç, Uğur
dc.date.accessioned2025-01-27T20:50:20Z
dc.date.available2025-01-27T20:50:20Z
dc.date.issued2023
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: We aimed to determine the scolicidal effect of hypochlorous acid and its efficiency at different concentrations. Materials and Methods: We tested the effectiveness of hypochlorous acid in-vitro on sterile gauze at different concentrations in test tubes. In addition, we compared its effectiveness with the scolicidal activity of other agents, povidone-iodine 10% and chlorhexidine-gluconate 0.04%. Results: Hypochlorous acid was 100% effective in 5 minutes at 1/1 (200 ppm/mL), 1/10 (20 ppm/mL), and 1/100 (2 ppm/mL) concentrations and in 10 minutes at 1/1000 (0.2 ppm/ mL) concentration. Povidone-iodine 10%, and chlorhexidine-gluconate 0.04% were studied undiluted and were effective at all study times. Hypochlorous acid maintained the same scolicidal activity on gauze at all study times at the described dilutions. Conclusion: Hypochlorous acid is an effective scolicidal agent in 5 minutes at even 1/100 concentrations. In addition, it maintains the same scolicidal activity on gauze used in surgery to wall the surgical site.
dc.description.sponsorshipCanakkale Onsekiz Mart University, the Scientific Research Coordination Unit [3692]
dc.description.sponsorshipThis work was financially supported by a grant from Canakkale Onsekiz Mart University, the Scientific Research Coordination Unit (Project number: 3692)
dc.identifier.doi10.36519/idcm.2023.238
dc.identifier.endpage164
dc.identifier.issn2667-646X
dc.identifier.issue2
dc.identifier.pmid38633006
dc.identifier.startpage158
dc.identifier.trdizinid1183926
dc.identifier.urihttps://doi.org/10.36519/idcm.2023.238
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1183926
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25472
dc.identifier.volume5
dc.identifier.wosWOS:001162999200003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherDoc Design Informatics Co Ltd
dc.relation.ispartofInfectious Diseases and Clinical Microbiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjecthypochlorous acid
dc.subjecthydatid disease
dc.subjectEchinococcus granulosus
dc.subjectscolicidal
dc.subjectnovel
dc.titleHypochlorous Acid: A Novel Agent Against Echinococcus granulosus Protoscoleces
dc.typeArticle

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