Effect of Fluorometholone/Tetrahydrozoline Fixed Combination on Conjunctival Autograft Morphology after Primary Pterygium Excision

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dc.authoridAgca, Alper/0000-0001-5435-075X
dc.authoriddemirok, ahmet/0000-0001-8197-2458
dc.authoridKara, Necip/0000-0001-8113-6206
dc.contributor.authorOzgurhan, Engin Bilge
dc.contributor.authorKara, Necip
dc.contributor.authorBozkurt, Ercument
dc.contributor.authorGencer, Baran
dc.contributor.authorAgca, Alper
dc.contributor.authorAlkin, Zeynep
dc.contributor.authorDemirok, Ahmet
dc.date.accessioned2025-01-27T20:49:27Z
dc.date.available2025-01-27T20:49:27Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose. To evaluate the effect of a fluorometholone/tetrahydrozoline fixed combination on conjunctival graft morphology after primary pterygium excision. Methods. The patients who underwent pterygium excision with conjunctival autograft transplantation were randomized into three groups based on postoperative medications as the fluorometholone/tetrahydrozoline group, fluorometholone group, and dexamethasone group. Conjunctival graft thickness was measured with anterior segment optical coherence tomography. The conjunctival graft hyperemia was evaluated using a high definition external camera. Results. The mean graft thickness was significantly lower in the fluorometholone/tetrahydrozoline group compared with fluorometholone and dexamethasone groups at 2 weeks (P = 0.002 and P = 0.012, resp.) and at 1 month after surgery (P = 0.003 and P = 0.013, resp.). The conjunctival hyperemia score was significantly lower in the fluorometholone/tetrahydrozoline group compared with fluorometholone and dexamethasone groups at 2 weeks (P = 0.000 and P = 0.000, resp.) and at 1 month (P = 0.039 and P = 0.040, resp.). The graft thickness and conjunctival hyperemia score were similar among the groups at 1 week and 3 months (P > 0.05). Conclusion. The findings of the present study revealed that treatment with the fluorometholone/tetrahydrozoline fixed combination may be helpful to decrease graft edema and to achieve better cosmetic appearance at 2 weeks and 1 month after pterygium excision.
dc.identifier.doi10.1155/2013/481843
dc.identifier.issn2314-6133
dc.identifier.issn2314-6141
dc.identifier.pmid23865053
dc.identifier.scopus2-s2.0-84880150664
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1155/2013/481843
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25160
dc.identifier.volume2013
dc.identifier.wosWOS:000321382300001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherHindawi Ltd
dc.relation.ispartofBiomed Research International
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectOptical Coherence Tomography
dc.subjectFibrin Glue
dc.subjectMitomycin-C
dc.subjectSurgery
dc.subjectTransplantation
dc.subjectClosure
dc.titleEffect of Fluorometholone/Tetrahydrozoline Fixed Combination on Conjunctival Autograft Morphology after Primary Pterygium Excision
dc.typeArticle

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