Evaluation of the risk of atherosclerosis in patients with adrenal incidentaloma using the ultrasound biomarkers EFT and CIMT

Basit Öğe Kaydı
dc.contributor.authorŞen, Hacer
dc.contributor.authorUysal, Fatma
dc.contributor.authorBinnetoğlu, Emine
dc.contributor.authorAşik, Mehmet
dc.contributor.authorErbağ, Gökhan
dc.contributor.authorGüneş, Fahri
dc.contributor.authorEroğlu, Mustafa
dc.date.accessioned2025-01-27T19:05:51Z
dc.date.available2025-01-27T19:05:51Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: Adrenal incidentalomas (AIs) are masses frequently observed on radiological examination that have attracted attention due to their coincidence with metabolic disorders. Recently, the relationship between atherosclerosis and adrenal incidentalomas has been noted. Epicardial fat tissue (EFT) and carotid artery intima-media thickness (CIMT) measurements show the development of atherosclerosis (AS). The aim of this study is to evaluate the risk of cardiovascular disease in AI patients using EFT and CIMT readings. Materials and methods: Our study included 63 AI patients and 48 healthy controls. All patients were evaluated for blood pressure, Body Mass Index(BMI), EFT, CIMT, and lipid parameters. AI patients were also investigated for hormonal secretion. The relationship between risk of atherosclerosis and EFT, CIMT was analyzed. Results: Control subjects (mean EFT, 3.92 ± 1.14 mm) had lower EFT than patients with subclinical Cushing's syndrome (SCS) and non-functional adenoma (NFA) (mean EFT, 6.22 ± 1.97 mm and 5.44 ± 1.61 mm, respectively) (both P < 0.001). There was no difference in EFT between SCS and NFA patients. CIMT was significantly lower in control subjects (mean CIMT, 0.65 ± 0.11 mm) than in NFA patients (mean CIMT, 0.75 ± 0.18 mm) (P < 0.01). The EFT of SCS patients was not significantly different from the EFT of either NFA patients or controls. Conclusion: EFT thickness measurements may be helpful as an early atherosclerosis marker in AI patients.
dc.identifier.endpage763
dc.identifier.issn0393-6384
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84944278682
dc.identifier.scopusqualityN/A
dc.identifier.startpage757
dc.identifier.urihttps://hdl.handle.net/20.500.12428/14011
dc.identifier.volume31
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherActa Medica Mediterranea
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectAdrenal incidentaloma; Atherosclerosis; Epicardial fat thickness
dc.titleEvaluation of the risk of atherosclerosis in patients with adrenal incidentaloma using the ultrasound biomarkers EFT and CIMT
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu