Evaluation of the risk of atherosclerosis in patients with adrenal incidentaloma using the ultrasound biomarkers EFT and CIMT
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Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Acta Medica Mediterranea
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction: Adrenal incidentalomas (AIs) are masses frequently observed on radiological examination that have attracted attention due to their coincidence with metabolic disorders. Recently, the relationship between atherosclerosis and adrenal incidentalomas has been noted. Epicardial fat tissue (EFT) and carotid artery intima-media thickness (CIMT) measurements show the development of atherosclerosis (AS). The aim of this study is to evaluate the risk of cardiovascular disease in AI patients using EFT and CIMT readings. Materials and methods: Our study included 63 AI patients and 48 healthy controls. All patients were evaluated for blood pressure, Body Mass Index(BMI), EFT, CIMT, and lipid parameters. AI patients were also investigated for hormonal secretion. The relationship between risk of atherosclerosis and EFT, CIMT was analyzed. Results: Control subjects (mean EFT, 3.92 ± 1.14 mm) had lower EFT than patients with subclinical Cushing's syndrome (SCS) and non-functional adenoma (NFA) (mean EFT, 6.22 ± 1.97 mm and 5.44 ± 1.61 mm, respectively) (both P < 0.001). There was no difference in EFT between SCS and NFA patients. CIMT was significantly lower in control subjects (mean CIMT, 0.65 ± 0.11 mm) than in NFA patients (mean CIMT, 0.75 ± 0.18 mm) (P < 0.01). The EFT of SCS patients was not significantly different from the EFT of either NFA patients or controls. Conclusion: EFT thickness measurements may be helpful as an early atherosclerosis marker in AI patients.
Açıklama
Anahtar Kelimeler
Adrenal incidentaloma; Atherosclerosis; Epicardial fat thickness
Kaynak
Acta Medica Mediterranea
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
31
Sayı
3
