Revolutionizing Dialysis: The Dual Impact of Incremental Peritoneal Dialysis on Patient Care and Sustainability

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dc.authorid0000-0002-3448-0490
dc.authorid0000-0001-6122-6829
dc.authorid0000-0002-2693-1167
dc.contributor.authorYildirim, Saliha
dc.contributor.authorAltunok, Murat
dc.contributor.authorYeter, Haci Hasan
dc.contributor.authorBakirdogen, Serkan
dc.contributor.authorCankaya, Erdem
dc.contributor.authorGuz, Galip
dc.date.accessioned2026-02-03T12:00:41Z
dc.date.available2026-02-03T12:00:41Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIntroduction: Chronic kidney disease (CKD) significantly impacts global health, with dialysis patients often experiencing reduced quality of life. Incremental start peritoneal dialysis (INPD) has emerged as a promising individualized treatment strategy, offering potential benefits for both patient outcomes and environmental sustainability compared to the standard peritoneal dialysis (STPD). This study aimed to evaluate the impact of incremental start continuous ambulatory peritoneal dialysis (CAPD) on quality of life, clinical outcomes, and environmental metrics, such as plastic waste generation, compared to conventional CAPD. Methods: A multicenter study involving two groups (incremental start CAPD - INPD and standard dose conventional CAPD - STPD groups) was conducted. The baseline and 6-month follow-up data were collected, including laboratory parameters, treatment-related plastic waste, glucose load, residual renal function, and quality of life assessed using the Kidney Disease Quality Of Life Short Form (KDQOL-SF). Results: There was no statistically significant difference in median age and gender between the two groups (p > 0.05). In the third month of the study, a significant difference was observed in peritoneal equilibrium test ultrafiltration volume, with higher values in the STPD group (p = 0.020). There were no statistically significant differences between study groups according to permeability groups (p = 0.714) or KtV (p = 0.743). In the sixth month of the study, the INPD group demonstrated significantly better residual renal function (p < 0.001) and reduced weekly polypropylene and polyvinyl chloride plastic waste (p < 0.001) and glucose load (p < 0.001) in both the baseline and sixth months of the study. KDQOL-SF scores were significantly higher in the INPD group (p < 0.001). Conclusion: INPD demonstrated superior outcomes in maintaining residual renal function, reducing treatment burden, and improving quality of life while significantly lowering environmental impact compared to STPD. These findings support the adoption of INPD as an individualized and sustainable strategy in CKD management. Further research is needed to validate these findings in larger cohorts and explore long-term outcomes.
dc.identifier.doi10.1159/000548852
dc.identifier.issn0253-5068
dc.identifier.issn1421-9735
dc.identifier.pmid41100430
dc.identifier.scopus2-s2.0-105027561194
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1159/000548852
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34661
dc.identifier.wosWOS:001619843300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofBlood Purification
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20260130
dc.subjectChronic kidney disease
dc.subjectIncremental peritoneal dialysis
dc.subjectPlastic waste
dc.subjectQuality of life
dc.titleRevolutionizing Dialysis: The Dual Impact of Incremental Peritoneal Dialysis on Patient Care and Sustainability
dc.typeArticle

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