Circulating cell free DNA and miRNA Amount in Congenital Hearing Loss

Basit Öğe Kaydı
dc.contributor.authorÇağlar, Özge
dc.contributor.authorÇayır, Akın
dc.contributor.authorCılgın, Begum
dc.contributor.authorDereköy, F. Sefa
dc.date.accessioned2025-01-27T19:43:28Z
dc.date.available2025-01-27T19:43:28Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Our aim is to detect the amount of miRNA and free DNA in the peripheral blood of young people with congenital hearing loss and compare this with control group.Materials and Methods: In our study, 16 patients who have congenital hearing lossand go to the private school for deaf children and 16 healthy individuals were select-ed in the same age group. 5 cc blood was taken from peripheral vessels of each individual. We compared the circulating cell-free DNA and miRNA amount with the results of the control group.Results: The ccfDNA amount of the patients with hearing loss was lower than thecontrol group and It was statistically significant. On the contrary, we found the high-er amount of ccfmiRNA in plasma samples of the patients with hearing loss. The statistical analysis showed that ccfmiRNA amount in congenital loss is consistently sig-nificantly higher than the control group.Conclusion: The miRNA and freeDNA can be used early in the diagnosis of congenital hearing loss.
dc.identifier.endpage23
dc.identifier.issn2147-9488
dc.identifier.issue3
dc.identifier.startpage19
dc.identifier.trdizinid314144
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/314144
dc.identifier.urihttps://hdl.handle.net/20.500.12428/17996
dc.identifier.volume49
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofActa Medica
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectGenel ve Dahili Tıp
dc.subjectOdyoloji ve Konuşma-Dil Patolojisi
dc.titleCirculating cell free DNA and miRNA Amount in Congenital Hearing Loss
dc.typeArticle

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu