Investigation of Raman, FT-IR, EPR spectra and antimicrobial activity of 2-(5-H/Me/Cl-1H-benzimidazol-2-yl)-phenol ligands and their Fe(NO3)3 complexes
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Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
2-(5-H/Me/Cl-1H-benzimidazol-2-yl)-phenol ligands form 1:1 electrolytes, 5-coordinate monometallic complexes with iron(III) nitrate. The geometry of the [Fe(L)(OH)(H2O)(2)](NO3) complexes was derived from theoretical calculation in DGauss/DFT level (DZVP basis set) on CACHE. In all of the complexes the ligands are bidentate, via one imine nitrogen atom and phenolate oxygen atom. The coordination is completed with a hydroxide ion, and two water molecules, adopting a distorted square pyramidal geometry. The structures of the compounds were confirmed on the basis of elemental analysis, molar conductivity, magnetic moment, FT-Raman, FT-IR (mid-IR, far-IR), EPR and u.v.-vis. The antimicrobial activities of the free ligands, their hydrochloride salts, and the complexes were evaluated using the disk diffusion method in dimethyl sulfoxide (DMSO) as well as the minimal inhibitory concentration (MIC) dilution method, against nine bacteria and the results are compared with several known antibiotic agents. Antifungal activities were reported for Candida albicans, Kluyveromyces fragilis, Rhodotorula rubra, Debaryomyces hansenii, Hanseniaspora guilliermondii, and the results were referenced against nystatin, ketaconazole, and clotrimazole antifungal agents. In most cases, the compounds tested showed broad-spectrum (Gram(+) & Gram(-) bacteria) activities that were either more active or as potent as the references.
Açıklama
Anahtar Kelimeler
Electron-Paramagnetic-Resonance, Transition-Metal Complexes, Structural-Characterization, Iron(Iii) Complexes, Optical-Absorption, Crystal-Structures, Fe(Iii) Ions, Derivatives, Pd(Ii), Benzimidazole
Kaynak
Transition Metal Chemistry
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
32
Sayı
2
