The Effect of Dehydration and Fasting on Corneal Biomechanical Properties and Intraocular Pressure

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dc.authoridSatirtav, Gunhal/0000-0003-4157-2876
dc.contributor.authorOltulu, Refik
dc.contributor.authorSatirtav, Gunhal
dc.contributor.authorErsan, Ismail
dc.contributor.authorSoylu, Erkan
dc.contributor.authorOkka, Mehmet
dc.contributor.authorZengin, Nazmi
dc.date.accessioned2025-01-27T20:47:53Z
dc.date.available2025-01-27T20:47:53Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: To evaluate the changes in corneal biomechanical properties and intraocular pressure (IOP) during fasting period in healthy subjects. Methods: Seventy-two eyes of 72 fasting subjects (study group), and 62 eyes of 62 nonfasting subjects (control group) were enrolled in this prospective study undertaken at a single university hospital. All subjects underwent complete ophthalmologic examination including ocular biomechanical evaluation with ocular response analyzer. Ocular response analyzer measurement was performed on the right eyes of the subjects between 5.00 and 6.00 PM after approximately 14 hr of fasting for the study group and after a nonfasting period for the control group. The corneal hysteresis, corneal resistance factor, mean corneal compensated IOP (IOPcc), and Goldmann-correlated IOP (IOPg) values were measured with a patented dynamic bidirectional applanation process. Results: Goldmann-correlated IOP and IOPcc measurements in the study group and the control group were found as 13.8 +/- 2.8 mm Hg, 14.6 +/- 2.6 mm Hg and 16.3 +/- 2.2 mm Hg, 15.7 +/- 2.4 mm Hg, respectively. There was statistically significant difference within the two groups in IOPg and IOPcc (P < 0.001). In addition, corneal hysteresis and corneal resistance factor significantly decreased in study group compared with control group (P < 0.001, P = 0.012, respectively). Conclusion: Prolonged fasting causes a significant decrease in IOPg, IOPcc, corneal hysteresis, and corneal resistance factor in healthy subjects, altering the biomechanical properties of the cornea.
dc.identifier.doi10.1097/ICL.0000000000000220
dc.identifier.endpage394
dc.identifier.issn1542-2321
dc.identifier.issn1542-233X
dc.identifier.issue6
dc.identifier.pmid26657661
dc.identifier.scopus2-s2.0-84949595581
dc.identifier.scopusqualityQ1
dc.identifier.startpage392
dc.identifier.urihttps://doi.org/10.1097/ICL.0000000000000220
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25077
dc.identifier.volume42
dc.identifier.wosWOS:000387490000011
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofEye & Contact Lens-Science and Clinical Practice
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectCorneal biomechanics
dc.subjectOcular response analyzer
dc.subjectRamadan month
dc.subjectFasting
dc.titleThe Effect of Dehydration and Fasting on Corneal Biomechanical Properties and Intraocular Pressure
dc.typeArticle

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