Electrochemical study of natamycin - analytical application to pharmaceutical dosage forms by differential pulse voltammetry

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dc.authoridDilgin, Yusuf / 0000-0002-2980-6871
dc.authoridYılmaz, Selehattin / 0000-0003-4607-3523
dc.contributor.authorAkı, Cüneyt
dc.contributor.authorYılmaz, Selehattin
dc.contributor.authorDilgin, Yusuf
dc.contributor.authorYağmur, S.
dc.contributor.authorSüren, E.
dc.date.accessioned2025-01-27T21:21:35Z
dc.date.available2025-01-27T21:21:35Z
dc.date.issued2005
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe electrochemical oxidation and determination of natamycin has been carried out at a carbon paste electrode in aqueous solutions in the pH range of 2.5-10.30 by cyclic and differential pulse voltammetry. Best results were obtained with the differential pulse voltametric technique in 0.5 M sulfuric acid at pH 1.82. The diffusion controlled nature of the waves was established. A differential pulse voltammetric technique for the determination of natamycin 0.5 M sulfuric acid which allows quantitation over the range of 2 x 10(-6)-8 x 10(-5) M range method is proposed. Limit of detection and limit of quantitatification were 1.5 x 10(-6) and 5 x 10(-6) M, respectively. Based on this study a simple, rapid, selective and sensitive voltammetric method was developed for the determination of natamycin in capsules. In order to validate the proposed method, UV spectroscopy was applied.
dc.identifier.endpage750
dc.identifier.issn0031-7144
dc.identifier.issue10
dc.identifier.pmid16259121
dc.identifier.scopus2-s2.0-27144468064
dc.identifier.scopusqualityQ3
dc.identifier.startpage747
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28999
dc.identifier.volume60
dc.identifier.wosWOS:000232585400005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherGovi-Verlag Pharmazeutischer Verlag Gmbh
dc.relation.ispartofPharmazie
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.titleElectrochemical study of natamycin - analytical application to pharmaceutical dosage forms by differential pulse voltammetry
dc.typeArticle

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