Evaluation of ocular surface epithelial and stromal thicknesses in psoriasis using anterior segment optical coherence tomography

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dc.authoridErsan, Ismail/0000-0003-0509-1661
dc.contributor.authorErsan, Ismail
dc.contributor.authorKilic, Sevilay
dc.contributor.authorIsik, Selda
dc.date.accessioned2025-01-27T20:26:57Z
dc.date.available2025-01-27T20:26:57Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose To evaluate the epithelial and stromal thicknesses of conjunctiva and cornea in psoriatic patients with anterior segment optical coherence tomography (AS-OCT), Methods In this cross-sectional study, 61 patients with psoriasis and 42 age-matched, healthy individuals were enrolled. The epithelial and stromal thicknesses of both inferotemporal bulbar conjunctiva and central cornea were measured using AS-OCT. Results Both the tear breakup time and Schirmer-1 test values were significantly lower in the psoriasis group compared with the controls (p < 0.05). The epithelial thickness of conjunctiva and cornea did not differ between psoriasis and control groups (p > 0.05). The central corneal stroma was significantly thicker in the psoriasis group (p = 0.04). PASI was positively correlated with the thickness of central cornea stroma (r = 0.442, p = 0.006) in the nail psoriasis group. Conclusions Psoriasis is not associated with altered epithelial thicknesses of the cornea and conjunctiva. It is accompanied by the stromal thickening of the cornea without conjunctival stromal involvement.
dc.identifier.doi10.1007/s10792-022-02289-3
dc.identifier.endpage3043
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue10
dc.identifier.pmid35389173
dc.identifier.scopus2-s2.0-85127688778
dc.identifier.scopusqualityQ2
dc.identifier.startpage3037
dc.identifier.urihttps://doi.org/10.1007/s10792-022-02289-3
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22519
dc.identifier.volume42
dc.identifier.wosWOS:000779669800002
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofInternational Ophthalmology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAnterior segment optical coherence tomography
dc.subjectDry eye
dc.subjectCornea
dc.subjectConjunctiva
dc.subjectEpithelium
dc.subjectPsoriasis
dc.subjectSystemic inflammation
dc.titleEvaluation of ocular surface epithelial and stromal thicknesses in psoriasis using anterior segment optical coherence tomography
dc.typeArticle

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