Sensitive voltammetric detection of acetaminophen at electropolymerized bromophenol red film-coated pencil graphite
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Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer Wien
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, a new sensitive electrochemical sensor was developed for the sensitive determination of acetaminophen (ACPN) at an electrochemically coated bromophenol red (PolyBFR) modified pencil graphite electrode (PGE). The modified electrode (PolyBFR-PGE) displayed a considerable increase in electrochemical response for the oxidation of ACPN, compared to the unmodified PGE. The electrochemical behavior of ACPN was determined by cyclic voltammetry and linear sweep voltammetry methods at PolyBFR-PGE. The effect of some parameters on the voltammetric response (monomer concentration, cycle number, and pH) was optimized for the voltammetric determination of ACPN. PolyBFR-PGE determines the ACPN in a wide linear segment from 0.25 to 3500 mu M. Furthermore, the limit of detection and sensitivity were found as 0.088 mu M ACPN and 1421.4 mu A mM(-1) cm(-2), respectively. The designed voltammetric ACPN sensor was successfully applied to pharmaceutical formulations and artificial samples, and satisfactory results were obtained with high accuracy and precision. [GRAPHICS] .
Açıklama
Anahtar Kelimeler
Bromophenol red, Acetaminophen, Voltammetry, Pencil graphite electrode, Sensors, Cyclic voltammetry
Kaynak
Monatshefte Fur Chemie
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
154
Sayı
10
