Olfactory Dysfunction in Patients with Ischemic Heart Failure

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dc.contributor.authorAksit, Ercan
dc.contributor.authorCil, Ozge Caglar
dc.date.accessioned2025-01-27T20:52:32Z
dc.date.available2025-01-27T20:52:32Z
dc.date.issued2020
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Heart failure (HF) is one of the leading causes of morbidity and mortality in the elderly. Early recognition, treatment, and elimination of potentially modifiable risk factors for HF are crucial for improving both survival and health-related life quality in those with HF. We aimed to investigate whether or not there is an association between olfactory function and the presence and severity of ischemic HF. Methods: The study included 40 patients with ischemic HF and 40 controls with coronary artery disease but without HF. All patients and controls underwent detailed physical and echocardiographic examinations. The Sniffin' Stick test was used to evaluate olfactory function. Results: Threshold-discrimination-identification (TDI) score was significantly lower in the patients with HF than in the controls (16.4 +/- 7.8 vs. 33.3 +/- 5.2, p < 0.001). When patients with ischemic HF were categorized according to New York Heart Association (NYHA) class, the TDI scores were significantly higher in the patients with NYHA class 1 HF compared to those with NYHA class 3 HF (23.4 +/- 0.9 vs. 8.8 +/- 7.0, p <0.001). We also found a significant negative correlation between the TDI score and NYHA class (r = -0.769, p < 0.001) and a positive correlation between the TDI score and left ventricular ejection fraction (r = 0.902, p < 0.001). Conclusions: Olfactory function was severely impaired in the patients with ischemic HF in this study. In addition, olfactory dysfunction in the patients with ischemic HF was significantly correlated with the severity of HF.
dc.identifier.doi10.6515/ACS.202003_36(2).20190812B
dc.identifier.endpage139
dc.identifier.issn1011-6842
dc.identifier.issue2
dc.identifier.pmid32201464
dc.identifier.scopus2-s2.0-85082195399
dc.identifier.scopusqualityQ3
dc.identifier.startpage133
dc.identifier.urihttps://doi.org/10.6515/ACS.202003_36(2).20190812B
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25790
dc.identifier.volume36
dc.identifier.wosWOS:000518714700007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTaiwan Soc Cardiology
dc.relation.ispartofActa Cardiologica Sinica
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectCerebral hypoperfusion
dc.subjectCoronary artery disease
dc.subjectHeart failure
dc.subjectOlfactory dysfunction
dc.subjectSeverity
dc.titleOlfactory Dysfunction in Patients with Ischemic Heart Failure
dc.typeArticle

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