Endoloop Versus LigaSure for Appendiceal Stump Closure in Pediatric Laparoscopic Appendectomy: A Multicenter Prospective Trial

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dc.authoridKaya Terzi, Neslihan / 0000-0001-8184-4691
dc.authoridKurtuluş, Şenay / 0000-0002-2178-2967
dc.contributor.authorKurtuluş, Şenay
dc.contributor.authorSuzen, Alev
dc.contributor.authorKaya Terzi, Neslihan
dc.contributor.authorÇelik, Serkan Yaşar
dc.date.accessioned2026-02-03T12:00:35Z
dc.date.available2026-02-03T12:00:35Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Appendiceal stump closure is critical in laparoscopic appendectomy (LA) to prevent complications such as stump leakage and intra-abdominal abscess formation. This study aims to evaluate the safety and effectiveness of LigaSure™ versus Endoloop for appendiceal stump closure in pediatric LA. Methods: This prospective multicenter comparative study included 199 pediatric patients who underwent LA between May 2021 and October 2023 at two pediatric surgery clinics. Patients were allocated to the LigaSure group (n = 74) or Endoloop group (n = 125) based on the surgeon’s intraoperative preference. Data collected included demographic characteristics, laboratory and radiological findings, intraoperative details, postoperative complications, and histopathological measurements of appendiceal and lumen diameters. Statistical analyses were performed using the independent samples t-test and chi-square test, with significance at P < .05. Results: No significant differences were observed between groups regarding age (P = .670), gender (P = .439), leukocyte count (P = .072), or C-reactive protein levels (P = .368). Complicated appendicitis was more prevalent in the LigaSure group (12.2%) compared to the Endoloop group (5.6%). No intra-abdominal abscesses or stump leakage were reported in either group. Histopathological analysis revealed no significant difference in mean appendiceal diameter (LigaSure: 8.9 ± 0.2 mm; Endoloop: 8.9 ± 0.1 mm; P = .743) or lumen diameter (P = .096). The largest lumen diameter measured in appendix specimens was 5113 μm, while the smallest was 255.6 μm (P = .096). No cases of intra-abdominal abscess or stump leakage were reported. The mean hospital stay was comparable (LigaSure: 2 ± 0.2 days; Endoloop: 2 ± 0.1 days; P = .068). Conclusion: LigaSure™ is a safe and effective alternative to Endoloop for appendiceal stump closure in pediatric LA. The device’s ability to provide a secure seal makes it a reliable option, even in cases of complicated appendicitis.
dc.identifier.doi10.1177/10926429251382515
dc.identifier.endpage833
dc.identifier.issn1092-6429
dc.identifier.issn1557-9034
dc.identifier.issue10
dc.identifier.pmid41043979
dc.identifier.scopus2-s2.0-105018708230
dc.identifier.scopusqualityQ2
dc.identifier.startpage828
dc.identifier.urihttps://doi.org/10.1177/10926429251382515
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34649
dc.identifier.volume35
dc.identifier.wosWOS:001587318000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMary Ann Liebert, Inc
dc.relation.ispartofJournal of Laparoendoscopic & Advanced Surgical Techniques
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WOS_20260130
dc.subjectLaparoscopic appendectomy
dc.subjectappendiceal stump closure
dc.subjectLigaSure (TM)
dc.subjectEndoloop
dc.titleEndoloop Versus LigaSure for Appendiceal Stump Closure in Pediatric Laparoscopic Appendectomy: A Multicenter Prospective Trial
dc.typeArticle

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