Quality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey

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dc.authoridSAHIN, AHMET/0000-0002-8377-8293
dc.authoridMUTLU YILMAZ, Esmeray/0000-0003-2569-7601
dc.authoridSahin, Ahmet Melih/0000-0003-3670-7801
dc.authoridbalkan, ilker/0000-0002-8977-5931
dc.authoridDurdu, Yasemin/0000-0003-3765-8108
dc.authoridSENEL, ILKNUR/0000-0003-0247-8772
dc.authoridSahin, Ahmet Ziyaettin/0000-0003-1060-6746
dc.contributor.authorKaracaer, Zehra
dc.contributor.authorCakir, Banu
dc.contributor.authorErdem, Hakan
dc.contributor.authorUgurlu, Kenan
dc.contributor.authorDurmus, Gul
dc.contributor.authorInce, Nevin Koc
dc.contributor.authorOzturk, Cinar
dc.date.accessioned2025-01-27T20:43:57Z
dc.date.available2025-01-27T20:43:57Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: The aim of this study was to assess health-related quality of life (HRQOL) among chronic hepatitis B (CHB) patients in Turkey and to study related factors. Methods: This multicenter study was carried out between January 01 and April 15, 2015 in Turkey in 57 centers. Adults were enrolled and studied in three groups. Group 1: Inactive HBsAg carriers, Group 2: CHB patients receiving antiviral therapy, Group 3: CHB patients who were neither receiving antiviral therapy nor were inactive HBsAg carriers. Study data was collected by face-to-face interviews using a standardized questionnaire, Short Form-36 (SF-36) and Hepatitis B Quality of Life (HBQOL). Values equivalent to p < 0.05 in analyses were accepted as statistically significant. Results: Four thousand two hundred fifty-seven patients with CHB were included in the study. Two thousand five hundred fifty-nine (60.1 %) of the patients were males. Groups 1, 2 and 3, consisted of 1529 (35.9 %), 1721 (40.4 %) and 1007 (23.7 %) patients, respectively. The highest value of HRQOL was found in inactive HBsAg carriers. We found that total HBQOL score increased when antiviral treatment was used. However, HRQOL of CHB patients varied according to their socio-demographic properties. Regarding total HBQOL score, a higher significant level of HRQOL was determined in inactive HBV patients when matched controls with the associated factors were provided. Conclusions: The HRQOL score of CHB patients was higher than expected and it can be worsen when the disease becomes active. Use of an antiviral therapy can contribute to increasing HRQOL of patients.
dc.identifier.doi10.1186/s12955-016-0557-9
dc.identifier.issn1477-7525
dc.identifier.pmid27809934
dc.identifier.scopus2-s2.0-85009282225
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1186/s12955-016-0557-9
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24435
dc.identifier.volume14
dc.identifier.wosWOS:000386954300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBMC
dc.relation.ispartofHealth and Quality of Life Outcomes
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectChronic hepatitis B infection
dc.subjectQuality of life
dc.subjectThe Hepatitis B Quality of Life Instrument
dc.subjectTurkey
dc.titleQuality of life and related factors among chronic hepatitis B-infected patients: a multi-center study, Turkey
dc.typeArticle

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