Determination of Calcium Dobesilate by Differential Pulse Voltammetry at a Disposable Pencil Graphite Electrode

Basit Öğe Kaydı
dc.authoridGiray Dilgin, Didem/0000-0002-3487-3470
dc.contributor.authorDilgin, Didem Giray
dc.date.accessioned2025-01-27T20:32:04Z
dc.date.available2025-01-27T20:32:04Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractThe electrochemistry of calcium dobesilate was investigated by recording cyclic and differential pulse voltammograms at a disposable and inexpensive pencil graphite electrode (PGE). Cyclic voltammograms of calcium dobesilate recorded in 0.1 M HCl showed a pair of well-defined redox peaks at the PGE indicating excellent electro-chemical activity. The oxidation peak current of the calcium dobesilate was used for its determination by recording its differential pulse voltammograms. The anodic peak current increased linearly with the concentration of calcium dobesilate in the range from 0.2 to 100 mu M with a detection limit 0.065 mu M. Relative standard deviations of 2.0 and 1.1% for innerday and 3.6 and 2.0% for intraday precision were obtained for three successive determinations of 0.5 and 10 mu M calcium dobesilate, respectively, which indicates acceptable repeatability and reproducibility. This voltammetric method was also successfully applied to the direct determination of calcium dobesilate in pharmaceutical samples. The effect of various interfering compounds on the calcium dobesilate peak current was studied. Thus, an unmodified PGE provides a new, promising, and alternative method of achieving sensitive, inexpensive, and selective determination of calcium dobesilate.
dc.identifier.doi10.1080/00032719.2017.1323335
dc.identifier.endpage197
dc.identifier.issn0003-2719
dc.identifier.issn1532-236X
dc.identifier.issue1-2
dc.identifier.scopus2-s2.0-85032664686
dc.identifier.scopusqualityQ2
dc.identifier.startpage186
dc.identifier.urihttps://doi.org/10.1080/00032719.2017.1323335
dc.identifier.urihttps://hdl.handle.net/20.500.12428/23344
dc.identifier.volume51
dc.identifier.wosWOS:000416519900014
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofAnalytical Letters
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectCalcium dobesilate
dc.subjectdifferential pulse voltammetry
dc.subjectdisposable electrode
dc.subjectglassy carbon electrode
dc.subjectpencil graphite electrode
dc.titleDetermination of Calcium Dobesilate by Differential Pulse Voltammetry at a Disposable Pencil Graphite Electrode
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu