Effects of environmental hypercapnia on hemato-immunological parameters, carbonic anhydrase, and Na+, K+-ATPase enzyme activities in rainbow trout Oncorhynchus mykiss) tissues

Basit Öğe Kaydı
dc.authoridGurkan, Mert/0000-0001-7861-3999
dc.authoridYılmaz, Sevdan/0000-0002-4809-5809
dc.contributor.authorKaya, Hasan
dc.contributor.authorYılmaz, Sevdan
dc.contributor.authorGurkan, Mert
dc.contributor.authorHisar, Olcay
dc.date.accessioned2025-01-27T20:56:05Z
dc.date.available2025-01-27T20:56:05Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn this study, the effects of environmental hypercapnia on hemato-immunological parameters and the activities of respiratory enzymes such as carbonic anhydrase (CA) and Na+, K+-ATPase were investigated in rainbow trout (Oncorhynchus mykiss) tissues (gill, liver and kidney). Batches of 12 fish were exposed to 4.5mg L-1 (control) and 14mg L-1 CO2. No mortalities occurred during the 14days of the experimental period. Red blood cell (RBC), hemoglobin (Hb), and hematocrit (Ht) levels, and innate immune parameters such as nitro blue tetrazolium (NBT), lysozyme, and myeloperoxidase activities, and the melano-macrophage frequency were negatively affected by elevated CO2 levels. Patterns of change in CA activity differed among the gill, liver, and kidney. Compared with the activities of CA in the control group, the CA enzyme was significantly stimulated at day 7 in the gill tissue, whereas it was stimulated at day 14 of the experiment in the liver tissue of fish exposed to 14mg L-1 CO2 (P < 0.05). In contrast to the pattern of CA enzyme activities, the Na+, K+-ATPase enzymes were stimulated significantly in the liver after day 7 but inhibited in the kidney and gill (P < 0.05). These results suggest that a subchronic exposure to hypercapnia of rainbow trout tissues may lead to adaptive changes in the respiratory enzymes and negatively affects hemato-immunological parameters.
dc.description.sponsorshipScientific and Technological Council of Turkey (TUBITAK) [113O220]
dc.description.sponsorshipThis work was partially supported by The Scientific and Technological Council of Turkey (TUBITAK, Project Number: 113O220, coordinated by H Kaya).
dc.identifier.doi10.1080/02772248.2013.869332
dc.identifier.endpage1407
dc.identifier.issn0277-2248
dc.identifier.issn1029-0486
dc.identifier.issue8
dc.identifier.scopus2-s2.0-84896739339
dc.identifier.scopusqualityQ3
dc.identifier.startpage1395
dc.identifier.urihttps://doi.org/10.1080/02772248.2013.869332
dc.identifier.urihttps://hdl.handle.net/20.500.12428/26299
dc.identifier.volume95
dc.identifier.wosWOS:000331929100015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor & Francis Ltd
dc.relation.ispartofToxicological and Environmental Chemistry
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectenvironmental hypercapnia
dc.subjectrainbow trout
dc.subjecthematology
dc.subjectimmunology
dc.subjectcarbonic anhydrase
dc.subjectNa+
dc.subjectK+-ATPase
dc.subjectmelano-macrophage centers
dc.titleEffects of environmental hypercapnia on hemato-immunological parameters, carbonic anhydrase, and Na+, K+-ATPase enzyme activities in rainbow trout Oncorhynchus mykiss) tissues
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu