Is Neutrophil Lymphocyte Ratio an Indicator for Proteinuria in Chronic Kidney Disease?

Basit Öğe Kaydı
dc.contributor.authorBinnetoglu, Emine
dc.contributor.authorSengul, Erkan
dc.contributor.authorHalhalli, Gokcen
dc.contributor.authorDindar, Sevim
dc.contributor.authorSen, Hacer
dc.date.accessioned2025-01-27T20:24:47Z
dc.date.available2025-01-27T20:24:47Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractBackground: Recent studies have shown that neutrophil lymphocyte ratio (NLR) is a strong indicator in determining inflammation in cardiac and non-cardiac diseases. We aimed to evaluate the relationship between proteinuria and NLR in chronic kidney disease (CKD) patients without diabetes mellitus (DM). Methods: Between 2011 and 2012 files of a total of 1000 CKD patients attending outpatient clinic were retrospectively scanned. Patients with DM, chronic disease, malignancy or stage 5 CKD were excluded. After these patients were excluded, a total of 69 patients with stage 3 and 4 CKD were evaluated. Results: The study comprised 27 patients with CKD without proteinuria (Group 1), 42 patients with CKD and proteinuria (Group 2) and 30 healthy volunteers (Group 3). NLR was highest in Group 2 and this was statistically significant compared with the control group (p = 0.012). The platelet lymphocyte ratio (PLR) in Group 2 was higher than the control group at a significant level (p = 0.004). There was a moderate positive correlation found between proteinuria and NLR (p = 0.013, r = 0.3). There was a positive correlation found between proteinuria and PLR (p = 0.002, r = 0.306). Conclusion: In conclusion, NLR, a parameter easily found in routine blood counts of CKD patients, is a marker with prognostic value for the presence and degree of proteinuria. (C) 2014 Wiley Periodicals, Inc.
dc.identifier.doi10.1002/jcla.21715
dc.identifier.endpage492
dc.identifier.issn0887-8013
dc.identifier.issn1098-2825
dc.identifier.issue6
dc.identifier.pmid24659410
dc.identifier.scopus2-s2.0-84936770970
dc.identifier.scopusqualityQ1
dc.identifier.startpage487
dc.identifier.urihttps://doi.org/10.1002/jcla.21715
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22347
dc.identifier.volume28
dc.identifier.wosWOS:000344345200011
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherJohn Wiley & Sons Inc
dc.relation.ispartofJournal of Clinical Laboratory Analysis
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectchronic kidney disease
dc.subjectneutrophil lymphocyte ratio
dc.subjectproteinuria
dc.titleIs Neutrophil Lymphocyte Ratio an Indicator for Proteinuria in Chronic Kidney Disease?
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu