Evaluation of Platelet Distribution Width and Mean Platelet Volume in Patients With Carotid Artery Stenosis

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dc.authoridAdam, Gürhan / 0000-0003-0778-0882
dc.authoridReşorlu, Mustafa / 0000-0002-2941-8879
dc.contributor.authorAdam, Gürhan
dc.contributor.authorKoçak, Erdem
dc.contributor.authorÖzkan, Adile
dc.contributor.authorReşorlu, Mustafa
dc.contributor.authorÇınar, Celal
dc.contributor.authorBozkaya, Halil
dc.contributor.authorKurt, Tolga
dc.date.accessioned2025-01-27T20:25:03Z
dc.date.available2025-01-27T20:25:03Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPlatelets contribute to the pathogenesis of atherosclerosis. Platelet activation has been linked with increased mean platelet volume (MPV) and platelet distribution width (PDW). We investigated the association between PDW, MPW, and the degree of carotid artery stenosis (CS). Patients (n = 229) were divided into 3 groups according to the North American Symptomatic Carotid Endarterectomy Trial criteria. Demographic and clinical features were collected retrospectively. Correlation analysis showed a positive association between PDW and the degree of CS. However, there was no significant correlation between CS and MPV. Moreover, we observed that PDW and low-density lipoprotein cholesterol were independent predictors of the degree of CS. This study showed that PDW, not MPV, is related to the degree of CS. Platelet distribution width could be a useful biomarker for CS. Whether targeting PDW will be of clinical benefit remains to be established.
dc.identifier.doi10.1177/0003319714548682
dc.identifier.endpage378
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue4
dc.identifier.pmid25313243
dc.identifier.scopus2-s2.0-84927512236
dc.identifier.scopusqualityQ2
dc.identifier.startpage375
dc.identifier.urihttps://doi.org/10.1177/0003319714548682
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22420
dc.identifier.volume66
dc.identifier.wosWOS:000352783800011
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofAngiology
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectmean platelet volume
dc.subjectplatelet distribution width
dc.subjectcarotid artery stenosis
dc.titleEvaluation of Platelet Distribution Width and Mean Platelet Volume in Patients With Carotid Artery Stenosis
dc.typeArticle

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