p(AAm/TA)-based IPN hydrogel films with antimicrobial and antioxidant properties for biomedical applications

dc.authoridBitlisli, Behzat Oral/0000-0003-1950-712X
dc.contributor.authorŞahiner, Mehtap
dc.contributor.authorSağbaş, Selin
dc.contributor.authorBitlisli, Behzat Oral
dc.date.accessioned2025-01-27T21:01:38Z
dc.date.available2025-01-27T21:01:38Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractInterpenetrating polymer networks (IPN), either semi-IPN (s-IPN) or full IPN, based on a natural polymer tannic acid (TA) and synthetic poly(acrylamide) (p(AAm)) were prepared by incorporation of TA during p(AAm) hydrogel film preparation with and without crosslinking of TA simultaneously. The synthesis of p(AAm/TA) s-IPN and IPN hydrogels with different amounts of TA were prepared by concurrent use of redox polymerization and epoxy crosslinking. The p(AAm)-based hydrogels were completely degraded at 37.5 degrees C within 9 and 2 days at pHs 7.4 and 9, respectively. Biocompatibility of p(AAm), s-IPN, and IPN were tested with WST assay and double staining, they had 75% cell viability up to almost 20 mu g mL(-1) concentration against L929 fibroblast cell. Antioxidant properties of IPN and s-IPN hydrogels were investigated with a
dc.identifier.doi10.1002/app.41876
dc.identifier.issn0021-8995
dc.identifier.issn1097-4628
dc.identifier.issue16
dc.identifier.scopus2-s2.0-84921505295
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1002/app.41876
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27133
dc.identifier.volume132
dc.identifier.wosWOS:000348313800029
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWiley
dc.relation.ispartofJournal of Applied Polymer Science
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectbiomedical applications
dc.subjectbiomaterials
dc.subjectdrug delivery systems
dc.subjectgels
dc.subjecthydrophilic polymers
dc.titlep(AAm/TA)-based IPN hydrogel films with antimicrobial and antioxidant properties for biomedical applications
dc.typeArticle

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