Is Acrylate Co-monomer (Glubran-2) Useful in the Prevention of Prolonged Air Leaks After Pulmonary Lobectomy?

dc.contributor.authorAlar, Timucin
dc.contributor.authorCeylan, Kenan Can
dc.contributor.authorDuman, Elif
dc.contributor.authorUsluer, Ozan
dc.contributor.authorBasok, Oktay
dc.date.accessioned2025-01-27T21:01:34Z
dc.date.available2025-01-27T21:01:34Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractMany synthetic materials are being used in order to reduce the frequency of prolonged air leak (PAL) in thoracic surgical practice. This study presents our experience with the topical application of acrylate co-monomer (Glubran-2) as a synthetic tissue adhesive in an attempt to decrease troublesome postoperative air leaks in patients undergoing resection for non-small cell lung carcinoma. Of the 112 patients who had undergone resection for lung carcinoma, 69 patients having lobectomy or bilobectomy were included in this study. The application group (group A) consisted of 33 patients where a synthetic tissue adhesive (Glubran-2) was used and compared with the control group (group C, n=36) retrospectively. There was no difference between the groups regarding demographic details and operative variables. Both groups were compared in view to PAL, chest tube duration, in-hospital stay and hospital costs. There was no significant difference between group A (n=11, 33 %) and group C (n=6, 17 %) for the development of PAL (P=0.11). Hospital stay was 16.1 +/- 6.7 days in group A and 15.3 +/- 5.8 days in group C (P=0.66). The surgical cost was significantly higher in group A (is an element of 806 +/- 127) than the group C (is an element of 624 +/- 94) (P<0.001). There was no significant difference between the groups regarding overall hospital costs (P=0.41). In this study, the use of Glubran-2 following lung resection for non-small cell lung carcinoma did not decrease the incidence of PAL. Neither did it have a favorable effect concerning in-hospital stay nor did it decrease overall hospital costs while increasing surgical costs as expected.
dc.identifier.doi10.1007/s12262-012-0522-8
dc.identifier.endpage376
dc.identifier.issn0972-2068
dc.identifier.issn0973-9793
dc.identifier.issue5
dc.identifier.pmid24426479
dc.identifier.scopus2-s2.0-84886539636
dc.identifier.scopusqualityQ4
dc.identifier.startpage373
dc.identifier.urihttps://doi.org/10.1007/s12262-012-0522-8
dc.identifier.urihttps://hdl.handle.net/20.500.12428/27105
dc.identifier.volume75
dc.identifier.wosWOS:000328538700008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer India
dc.relation.ispartofIndian Journal of Surgery
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectLung cancer surgery
dc.subjectSurgery
dc.subjectComplications
dc.subjectLobectomy
dc.subjectPulmonary resection
dc.subjectLung cancer
dc.titleIs Acrylate Co-monomer (Glubran-2) Useful in the Prevention of Prolonged Air Leaks After Pulmonary Lobectomy?
dc.typeArticle

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