Sensitive Electrochemical Determination of Oxcarbazepine using Polymer Film Modified Glassy Carbon Electrode
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Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Esg
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A glassy carbon electrode (GCE) is modified with electropolymerized film of p-aminobenzene sulfonic acid (p-ABSA) in pH 7.0 phosphate buffer solution (PBS). A poly(p-ABSA) modified glassy carbon electrode was used for the voltammetric determination of oxcarbazepine. The modified electrode exhibited excellent electrocatalytic activity for the reduction of oxcarbazepine. The voltammetric response of oxcarbazepine at this polymer film modified electrode increased significantly when compared with that at a bare glassy carbon electrode. The proposed method was applied to the quantification of oxcarbazepine in pharmaceutical formulations. The proposed method exhibits good recovery and reproducibility. The mechanisms of electropolymerization of p-ABSA and reduction of oxcarbazepine are also suggested.
Açıklama
Anahtar Kelimeler
p-Aminobenzene sulfonic acid, Modified-glassy carbon electrode, Electropolymerization, Electrocatalytic-reduction, Determination of oxcarbazepine
Kaynak
International Journal of Electrochemical Science
WoS Q Değeri
Q3
Scopus Q Değeri
Q3
Cilt
10
Sayı
2