Sensitive Electrochemical Determination of Oxcarbazepine using Polymer Film Modified Glassy Carbon Electrode

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Tarih

2015

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Esg

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

A glassy carbon electrode (GCE) is modified with electropolymerized film of p-aminobenzene sulfonic acid (p-ABSA) in pH 7.0 phosphate buffer solution (PBS). A poly(p-ABSA) modified glassy carbon electrode was used for the voltammetric determination of oxcarbazepine. The modified electrode exhibited excellent electrocatalytic activity for the reduction of oxcarbazepine. The voltammetric response of oxcarbazepine at this polymer film modified electrode increased significantly when compared with that at a bare glassy carbon electrode. The proposed method was applied to the quantification of oxcarbazepine in pharmaceutical formulations. The proposed method exhibits good recovery and reproducibility. The mechanisms of electropolymerization of p-ABSA and reduction of oxcarbazepine are also suggested.

Açıklama

Anahtar Kelimeler

p-Aminobenzene sulfonic acid, Modified-glassy carbon electrode, Electropolymerization, Electrocatalytic-reduction, Determination of oxcarbazepine

Kaynak

International Journal of Electrochemical Science

WoS Q Değeri

Q3

Scopus Q Değeri

Q3

Cilt

10

Sayı

2

Künye