Yazar "Sadikoglu, M." seçeneğine göre listele

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    Electroanalytical Investigation of Paracetamol on Glassy Carbon Electrode by Voltammetry
    (Esg, 2015) Engin, C.; Yilmaz, S.; Saglikoglu, G.; Yagmur, S.; Sadikoglu, M.
    An electroanalytical method was developed for the direct quantitative determination of paracetamol (or acetaminophen) in tablet dosage forms based on its oxidation behavior. The electrochemical oxidation and determination of paracetamol were easily carried out on glassy carbon electrode (GCE) using a variety of voltammetric techniques. The electrochemical measurements were carried out on GCE in various buffer solutions in the pH range from 0.51 to 12.00 by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The dependence of pH on the anodic peak current and peak potential was investigated. Acetate buffer (pH 4.51) was selected for analytical purposes. Scan rate studies were also completed. The diffusion controlled nature of the peak was established. A linear calibration curve for DPV analysis was constructed in the paracetamol concentration range from 4x10(-6) mol/L to 1x10(-4) mol/L. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 3.69x10(-7) mol/L and 1.23x10(-6) mol/L respectively. Validation of applied voltammetric techniques was checked with recovery studies.
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    Electroanalytical investigation of paracetamol on glassy carbon electrode by voltammetry
    (Electrochemical Science Group, 2015) Engin, C.; Yilmaz, S.; Saglikoglu, G.; Yagmur, S.; Sadikoglu, M.
    An electroanalytical method was developed for the direct quantitative determination of paracetamol (or acetaminophen) in tablet dosage forms based on its oxidation behavior. The electrochemical oxidation and determination of paracetamol were easily carried out on glassy carbon electrode (GCE) using a variety of voltammetric techniques. The electrochemical measurements were carried out on GCE in various buffer solutions in the pH range from 0.51 to 12.00 by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The dependence of pH on the anodic peak current and peak potential was investigated. Acetate buffer (pH 4.51) was selected for analytical purposes. Scan rate studies were also completed. The diffusion controlled nature of the peak was established. A linear calibration curve for DPV analysis was constructed in the paracetamol concentration range from 4x10-6 mol/L to 1x10-4 mol/L. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 3.69x10-7 mol/L and 1.23x10-6 mol/L respectively. Validation of applied voltammetric techniques was checked with recovery studies. © 2015 The Authors.
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    Electrocatalytic oxidation of hydrazine on poly(4-aminobenzene sulfonic acid)-modified glassy carbon electrode
    (Pleiades Publishing Inc, 2016) Sadikoglu, M.; Yilmaz, S.; Kurt, I.; Selvi, B.; Sari, H.; Erduran, N.; Usta, E.
    Electrocatalytic oxidation of hydrazine (HZ) was studied on an stable modified glassy carbon electrode (GCE) based on poly (4-aminobenzene sulfonic acid) (4-ABSA) film. The 4-ABSA-modified glassy carbon electrode was prepared by electrochemical polymerization technique in phosphate buffer solution (PBS) (pH 7.0) and its electrochemical behavior were studied by cyclic voltammetry (CV). The polymer filmmodified electrode has very high catalytic ability for electrooxidation of HZ, which appeared as a reduced overpotential in a wide operational pH range of 5-10. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 1.31 x 10(-7) and 4.35 x 10(-7) M for CV; 7.89 x 10(-8) and 2.63 x 10(-7) M for CA, respectively. The results of experiments showed that prepared modified electrode have good stability, sensitivity and reproducibility for at least one month if stored dry in air.
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    Electrocatalytic Oxidation of Hydrazine on Poly(4-Aminobenzene Sulfonic Acid)-Modified Glassy Carbon Electrode (vol 52, pg 539, 2016)
    (Maik Nauka/Interperiodica/Springer, 2016) Sadikoglu, M.; Yilmaz, S.; Kurt, I.; Selvi, B.; Sari, H.; Erduran, N.; Usta, E.
    [Anstract Not Available]
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    Electrocatalytic oxidation of moxifloxacin hydrochloride on modified glassy carbon surface and determination in Avelox tablets
    (Bulgarian Academy of Sciences, 2019) Sadikoglu, M.; Soylu, U.I.; Yilmaz, S.; Selvi, B.; Yildiz Seckin, H.; Nosal-Wiercinska, A.
    This work presents an electroanalytical method for the determination of moxifloxacin hydrochloride (MOX) in tablets. The surface of the glassy carbon electrode (GCE) was modified by electrochemical polymerization of 4-aminobenzene sulfonic acid in phosphate buffer solution (pH 7.0).The oxidative behavior of MOX was studied at glassy carbon and modified glassy carbon electrodes in different buffer systems using the cyclic voltammetry technique. The modified glassy carbon electrode (poly(4-ABSA/GCE) has very high catalytic ability for electrooxidation of MOX. Acetate buffer (pH 5.0) was selected as the optimum medium for the oxidation of MOX at poly(4-ABSA/GCE) due to the highest electronic signal increase obtained. Differential pulse voltammetry (DPV) and chronoamperometry (CA) techniques were used for voltammetric determination of MOX. The values of limit of detection (LOD) and limit of quantification (LOQ) were determined to be 3.19×10 -7 M and 1.06×10 -6 M for DPV; and 5.50×10 -7 M and 1.83×10 -6 M for CA, respectively. A highly sensitive electroanalytical method for the determination of MOX in Avelox tablets by DPV was described. © 2019 Bulgarian Academy of Sciences, Union of Chemists in Bulgaria
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    Electrooxidation of Phenazopyridine Hydrochloride and its Voltammetric and HPLC Determination in Human Urine and Tablet Dosage Form
    (Esg, 2013) Yagmur, S.; Yilmaz, S.; Sadikoglu, M.; Saglikoglu, G.; Yildiz, M.; Yengin, C.; Kilinc, E.
    The electrochemical oxidation of phenazopyridine hydrochloride (PAP) was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques at ultra trace graphite electrode (UTGE). PAP exhibited a diffusion controlled process which is pH dependence. The dependence of the current and potential on pH, the concentration and nature of buffer, and scan rate was investigated to optimize the experimental conditions for the determination of PAP. It was found that the optimum buffer for the determination of PAP is 0.1 NaOH solutions with the pH 12.97. In the concentration range from 6.0x10(-8) to 1.0x10(-6) M, the current measured by DPV present a good linear property as a function of the concentration of PAP. Limit of detection (LOD) and limit of quantification (LOQ) were obtained as 8.1x10(-10) and 2.7x10(-9) M, respectively. PAP was determined in human urine and tablet dosage form. Precision and accuracy of the developed technique were checked by recovery studies in spiked urine and tablet dosage form. In addition, for the comparison, high performance liquid chromatography (HPLC) technique was applied for the determination of PAP in the same samples.
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    The Quantitative Detection of Phenylephrine in Pharmaceutical Preparations and Spiked Human Urine by Voltammetry
    (Pleiades Publishing Inc, 2018) Yagmur, S.; Ture, M.; Saglikoglu, G.; Sadikoglu, M.; Yilmaz, S.
    A voltammetric method was used for the quantitative detection of phenylephrine in pharmaceutical preparations and spiked human urine. The electrochemical measurements were carried out in various buffer solutions in the pH range from 0.51 to 12.00 on ultra-trace graphite electrode (UTGE) by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. The dependence of pH on the oxidation peak current and peak potential was investigated. Britton-Robinson buffer (pH 8.02) was selected for analytical purposes. The peak was established to be diffusion controlled nature of electrode. A linear calibration curve for DPV analysis was constructed in the phenylephrine concentration range from 8 x 10(-6) to 1 x 10(-4) M. Limits of detection (LOD) and quantification (LOQ) were obtained as 2.07 x 10(-7) M and 6.91 x 10(-6) M respectively. The repeatability, accuracy and precision of the developed technique were checked in spiked urine and pharmaceutical preparations.