Diagnostic Value of Plasma Pentraxin3-Level For Diagnosis of Erectile Dysfunction

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dc.authoridAlan, Cabir/0000-0002-6024-4475
dc.contributor.authorEren, Ali Erhan
dc.contributor.authorErsay, Ahmet Resit
dc.contributor.authorDemirci, Emrah
dc.contributor.authorAlan, Cabir
dc.contributor.authorBasturk, Gokhan
dc.date.accessioned2025-01-27T20:23:14Z
dc.date.available2025-01-27T20:23:14Z
dc.date.issued2018
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: Erectile dysfunction (ED) is a sexual dysfunction described as the inability to develop or maintain an erection of the penis adequate for sexual intercourse, and its prevalence increases with age. Seen as a common sexual disorder worldwide, organic causes are the underlying reason for 80 percent of ED cases, with the most characteristic pathology responsible for organic ED being atherosclerosis. This study investigates the diagnostic value of plasma PTX-3 levels in arterial ED. Materials and Methods: This study included a total of 45 patients who were admitted to the urology and cardiology outpatient clinics of the Medical Faculty of Canakkale Onsekiz Mart University (COMU) and consented to participate in this study. Patients were categorized into three equal groups in number: (1) patients with ED diagnosed with coronary artery disease (CAD) (15 patients in total); (2) patients with ED not having coronary artery disease or any other equivalent diseases (diabetes mellitus, hypertension and hyperlipidemia) (15 patients in total); and (3) ordinary patients with no ED (15 patients in total). An interview was conducted at the andrology polyclinic with each patient in order to ascertain detailed information on their medical and sexual history and on demographic characteristics. All patients were also administered the International Index of Erectile Function (IIEF) questionnaire. Result: The findings from this study investigating the diagnostic value of plasma PTX-3 levels in ED were statistically significant for two comparisons: the differences between the peripheral blood and cavernous blood values of the patient groups (group 1 and 2) and the control group (group 3), and the differences between the peripheral blood and cavernous blood values of group 2 (patients with ED who do not have CAD) and the control group (group 3). Conclusion: As PTX-3 is more specific than the formerly recognized biochemical markers in endothelial dysfunction, it can be used in the diagnosis of vascular originated ED.
dc.identifier.endpage203
dc.identifier.issn1735-1308
dc.identifier.issn1735-546X
dc.identifier.issue4
dc.identifier.pmid29681053
dc.identifier.startpage199
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22153
dc.identifier.volume15
dc.identifier.wosWOS:000441478500009
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherUrol & Nephrol Res Ctr-Unrc
dc.relation.ispartofUrology Journal
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectatherosclerosis
dc.subjectcoronary artery disease
dc.subjecterectile dysfunction
dc.subjectpentraxin-3 (PTX-3)
dc.subjectsexual function
dc.titleDiagnostic Value of Plasma Pentraxin3-Level For Diagnosis of Erectile Dysfunction
dc.typeArticle

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