Characteristics of hospitalized COVID-19 patients and parameters associated with severe pneumonia

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Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

The European Respiratory Society

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objectives: The aim of this study is to analyse characteristics of hospitalized COVID-19 patients in Turkey. Methods: Hospitalized COVID-19 patients with positive naso-oropharyngeal swab examples from 10 different centers were included. Demographics, admission symptoms, laboratory and radiological findings were recorded retrospectively. Results: Of 1013 patients included in the study, there were 583 male (57.6%) and 430 female (42.4%), with the mean age of 53.7±17.9. More than half (%51.7) of the patients had at least one comorbid disease; the most common ones were hypertension and diabetes mellitus. Cough (59.8%), fatigue (49.5%) and fever (41.2%) were the most common presenting symptoms. There was pneumonia in 84.9% of hospitalized COVID-19 patients; 83.5% had typical radiological COVID-19 appearance (94.5%: ground glass areas). The most common laboratory findings were high CRP (73.6%) and lactat dehydrogenase (LDH) (46.2%) levels and lymphopenia (30.1%). Severe pneumonia was present in 28.1% of COVID-19 patients. Multivariate logistic regression analysis indicated that high age, hypotension, anemia, elevated serum levels of CRP and LDH were independent risk factors for severity of COVID-19 pneumonia (p=0.011, 0.006, 0.017, 0.003 and 0.001, respectively). Conclusion: Our study, which is one of the first multicenter studies about COVID-19 characteristics in Turkey, is thought to be a guide for COVID-19 patients in terms of clinical features . Age, blood pressure measurement, complete blood count and routine biochemical tests (including CRP and LDH) seem to be important parameters for evaluating the severity of pneumonia in COVID-19 patients.

Açıklama

This abstract was presented at the 2021 ERS International Congress, in session “Prediction of exacerbations in patients with COPD”.

Anahtar Kelimeler

Covid-19, Pneumonia, Biomarkers

Kaynak

European Respiratory Journal

WoS Q Değeri

Q1

Scopus Q Değeri

Cilt

58

Sayı

suppl 65

Künye

Turan, M. O., Mirici, A., Akçalı, S. D., Turan, P. A., Batum, Ö., Şengül, A., … Yılmaz, Ü. (2021). Characteristics of hospitalized COVID-19 patients and parameters associated with severe pneumonia. European Respiratory Journal, 58(suppl 65). doi: 10.1183/13993003.congress-2021.PA3254