Assessment of meibomian glands with topography in patients using unilateral antiglaucoma drops

dc.contributor.authorAlbakeri, Abdullah
dc.contributor.authorÇömez, Arzu Taşkıran
dc.date.accessioned2025-01-27T19:15:05Z
dc.date.available2025-01-27T19:15:05Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractPurpose: The study aims to evaluate the function and morphology of the meibomian glands and tear function tests in patients with unilateral glaucoma. Methods: The files of 1100 glaucoma patients attending, Ophthalmology clinic from 2014 to 2018 were screened. In total, 38 eyes from 38 out of 84 patients using antiglaucomatous agents in one eye who abided by the criteria and accepted participation were included in the study. After general ophthalmologic examination including best corrected visual acuity, biomicroscopic and ophthalmoscopic examination, ocular surface disease index (OSDI) survey, tear osmolarity, noninvasive tear breakup time (NITBUT), meibography (MEBG) and lower lid tear meniscus height (TMH) measurement, followed by Schirmer test and tear breakup time (TBUT) were measured, respectively. Results: With mean age of 68.6±12.8 years, 13 patients (34.3%) were female and 25 were male (65.7%). Mean duration of medication use was 37.97 months with mean OSDI score of 33.76±16.2 C4.10–77). The difference between NITBUT and atrophy percentage of meibomian glands in glaucomatous and control eyes was identified to be significant (NITBUT: 9.08±2.98; 12.01±4.30; p=0.001, MEBG 41.15%±14.04%, 28.33%±11.77%, p=0.001). A significant decrease was observed for TMH, TBUT and Schirmer test for eyes administered drops compared to control eyes (p=0.001; p=0.0001; p=0.009, respectively) and tear osmolarity was identified to be significantly high (p=0.0001). Conclusion: In addition to the negative effects of topical antiglaucomatous drops on tear aqueous components, patients should be monitored for dry eye findings as closely as for intraocular pressure and popularizing the use of preservative-free medications is important in terms of patients’ treatment compliance.
dc.identifier.doi10.14744/eer.2022.54264
dc.identifier.endpage8
dc.identifier.issn2757-8135
dc.identifier.issn2757-9816
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.trdizinid1165685
dc.identifier.urihttps://doi.org/10.14744/eer.2022.54264
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1165685
dc.identifier.urihttps://hdl.handle.net/20.500.12428/14705
dc.identifier.volume2
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofEuropean eye research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectMikroskopi
dc.subjectSolunum Sistemi
dc.subjectGöz Hastalıkları
dc.titleAssessment of meibomian glands with topography in patients using unilateral antiglaucoma drops
dc.typeArticle

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