Assessment of thyroid disease in patients who underwent surgical treatment of primary hyperparathyroidism

Purpose: In this study we aimed to evaluate thyroid pathologies in patients with primary hyperparathyroidism who underwent surgery for parathyroidectomy. Methods: Patients who underwent parathyroidectomy for primary hyperparathyroidism between the years of 2006-2012 were included in this retrospective study. Before and after surgery, hormonal and biochemical examinations of the patients and results of preoperative imaging studies were recorded. Results: Of the patients included in the study, 86 were female and 12 were male. Preoperative mean serum calcium level was 12.25 ± 1.48 mg/dL (normal range 8.5-10.1 mg/dL), mean parathyroid hormone (PTH) level was 425.09 ± 440.47 pg/mL (normal range 11-65 pg/mL). The thyroid ultrasound records of 93 patients were available. Of these patients, 26 (28%) had normal ultrasound, 18 (19.4%) had solitary nodule, 43 (46.2%) had multinodular goiter and 4 (4.3%) had thyroiditis (without nodule) and 2 (% 2.2) had solitary nodule with thyroiditis. Adenoma was detected by ultrasonography in 45.2 % of patients, and by scintigraphy in 72.7 of patients. Parathyroidectomy and thyroidectomy were performed at the same time in 54 of 98 patients (65.1%). Of these patients Seven (7.1%) had papillary thyroid cancer, 30 (30.6%) had benign multinodular goiter, 8 patients (8.2%) had benign solitary nodule, 2 patients (2%) had lymphocytic thyroiditis, and 7 (7.1%) had normal thyroid tissue. Conclusion: Thyroid diseases are frequently encountered with primary hyperparathyroidism. Therefore, before performing parathyroidectomy with minimally invasive procedure, patients must be evaluated for thyroid disorders. © 2012 Düzce Medical Journal.