A Case of Oxcarbazepine-Induced Severe Hyponatremia

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dc.contributor.authorDegirmenci, Yildiz
dc.contributor.authorYilmaz, Yeliz
dc.contributor.authorOrs, Ceyda Hayretdag
dc.contributor.authorKaraman, Handan Isin Ozisik
dc.date.accessioned2025-01-27T21:21:19Z
dc.date.available2025-01-27T21:21:19Z
dc.date.issued2011
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractOxcarbazepine is a keto-analogue of carbamazepine. Hyponatremia seen in the patients treated with oxcarbazepine is usually asymptomatic and rarely severe which leads to drug withdrawal. Here we presented a 51-year old female patient with epilepsy under oxcarbazepine and valproate treatment, who presented to our outpatient neurology clinic with vertigo, nausea and vomitting after the usage of her antiepileptic drugs. Routine biochemistry evluations revealed a decresed serum sodium level with increased urine sodium and osmolarity levels. Renal ultrasonography was normal. The patient was pre-diagnosed as inappropriate antidiuretic hormone secretion syndrome. Three days after the oxcarbazepine withdrawal, serum and urine sodium levels were found to be normal.
dc.identifier.doi10.5505/epilepsi.2011.02996
dc.identifier.endpage60
dc.identifier.issn1300-7157
dc.identifier.issue2
dc.identifier.startpage58
dc.identifier.urihttps://doi.org/10.5505/epilepsi.2011.02996
dc.identifier.urihttps://hdl.handle.net/20.500.12428/28898
dc.identifier.volume17
dc.identifier.wosWOS:000408823900004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherKare Publ
dc.relation.ispartofEpilepsi
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectHyponatremia
dc.subjectoxcarbazepine
dc.subjectinappropriate antidiuretic hormone secretion
dc.titleA Case of Oxcarbazepine-Induced Severe Hyponatremia
dc.typeArticle

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