Effects of perioperative statin treatment on postoperative atrial fibrillation and cardiac mortality in patients undergoing coronary artery bypass grafting: A propensity score analysis

Basit Öğe Kaydı
dc.contributor.authorKunt, Ayşegül
dc.contributor.authorÖzcan, Sedat
dc.contributor.authorKüçüker, Aslihan
dc.contributor.authorOdabaşi, Dolunay
dc.contributor.authorKunt, Alper Sami
dc.date.accessioned2025-01-27T18:58:50Z
dc.date.available2025-01-27T18:58:50Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim To evaluate the effect of perioperative statin treatment on postoperative atrial fibrillation and cardiac mortality in patients undergoing coronary artery bypass grafting. Methods A total of 1890 patients who underwent isolated coronary artery bypass were analyzed retrospectively, of which 425 patients (22.4%) older than 70 were included in the study. The demographic properties, preoperative, operative and postoperative data and other medications of these patients were recorded. Continuous preoperative and postoperative atorvastatin therapy were received by 124 (29.17%) patients; 301 (70.82%) patients were matched to a control group (no-statin group). The two groups were matched by propensity score analysis in terms of atrial fibrillation development and cardiac mortality. Results Medical history, medical treatment, cardiovascular history, and operative characteristics demonstrated significant heterogeneity in both groups. Postoperative atrial fibrillation was similar in both groups. Before propensity score matching, the percentages of patients in postoperative atrial fibrillation with respect to Ator- vastain-group and No-statin-group were 13.71 and 10.3 respectively; however, those were 13.71 and 14.51 after matching. In a multivariate regression analysis, five-vessel bypass (odds ratio OR, 2.354; 95% confidence interval CI, 0.99 to 5.57) was an independent predictor of postoperative atrial fibrillation in patients undergoing coronary artery bypass grafting. In-hospital mortality was higher in the Atorvastatin-group compared with the No-statin- group: 124 (8.9%) versus 301 (3.7%), respectively; p=0.027). Conclusion Perioperative atorvastatin treatment is not found to be associated with reduced postoperative atrial fibrillation and cardiac mortality in patients undergoing isolated coronary artery bypass grafting above the age of seventy years. © 2015, Medical Association of Zenica-Doboj Canton, All rights reserved.
dc.identifier.doi10.17392/796-15
dc.identifier.endpage195
dc.identifier.issn1840-0132
dc.identifier.issue2
dc.identifier.pmid26276658
dc.identifier.scopus2-s2.0-84954479560
dc.identifier.scopusqualityQ2
dc.identifier.startpage190
dc.identifier.urihttps://doi.org/10.17392/796-15
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13026
dc.identifier.volume12
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMedical Association of Zenica-Doboj Canton
dc.relation.ispartofMedicinski Glasnik
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectCardiac mortality; Coronary artery bypass grafting; Postoperative atrial fibrillation; Preoperative statin therapy; Propensity score analysis
dc.titleEffects of perioperative statin treatment on postoperative atrial fibrillation and cardiac mortality in patients undergoing coronary artery bypass grafting: A propensity score analysis
dc.typeArticle

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu