Investigation of the Synthesis, Antioxidant, DNA Binding and DNA Cleavage Properties of Sodium 2-((2-hydroxy-5-methylphenylimino) methyl) benzenesulfonate

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dc.contributor.authorDuman, Merve
dc.contributor.authorDemir, Neslihan
dc.contributor.authorYıldız, Mustafa
dc.contributor.authorDalgiç, Büşra
dc.date.accessioned2025-01-27T18:52:58Z
dc.date.available2025-01-27T18:52:58Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description2022 International Conference on Research in Education and Science, CRES 2022 -- 24 March 2022 through 27 March 2022 -- Antalya -- 185304
dc.description.abstractSulfonate is known as a salt or ester of a sulfonic acid. It contains the sulfonate functional group R-SO-3. They are stable in water, non-oxidizing and colorless. The interaction of sodium-2-formylbenzenesulfonate with 2-amino-4-methyl-phenol produced 2-((2-hydroxy-5-methylphenylimino) methyl) benzenesulfonate in this investigation. Nuclear Magnetic Resonance spectroscopy (NMR), Fourier Transform Infrared (FTIR) Spectroscopy, Ultraviolet visible spectroscopy (UV-Vis) and Mass Spectroscopy (MS) techniques were used to identify the properties of the compound. The antimicrobial activity of the schiff base was tested using the Minimum Inhibitor Concentration (MIC) method. The reaction of the compound with for DNA were identified by DNA Cleavage and DNA Binding methods. The compound was observed to reaction electrostatically with Calf Thymus-DNA (CT-DNA) and further cleaved it hydrolytic and oxidative. The antioxidant activity of the synthesized base was examined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) technique. It has been determined that as the concentration of the chemical increases, so does its antioxidant activity. © CRES 2022.All rights reserved.
dc.identifier.endpage189
dc.identifier.issn2833-6747
dc.identifier.issue1
dc.identifier.scopus2-s2.0-85145905483
dc.identifier.scopusqualityQ4
dc.identifier.startpage181
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12514
dc.identifier.volume8
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherThe International Society for Technology Education and Science
dc.relation.ispartofProceedings of International Conference on Research in Education and Science
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectDNA cleavage; DPPH; Minimum Inhibitory Concentration; Sodium benzenesulfonate; Spectroscopy
dc.titleInvestigation of the Synthesis, Antioxidant, DNA Binding and DNA Cleavage Properties of Sodium 2-((2-hydroxy-5-methylphenylimino) methyl) benzenesulfonate
dc.typeConference Object

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