İminopodand ve geçiş metal komplekslerinin sentezi, yapılarının aydınlatılması
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Tarih
2014
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Çanakkale Onsekiz Mart Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada 1,2-bis-(2-kloroetoksi)etan ile 4-nitrofenol' ün sodyum tuzunun DMF ortamındaki reaksiyonundan nitropodand (1), bu bileşiğin indirgenmesi ile de aminopodand (2) sentezlendi. Aminopodand 2 bileşiğinin sırasıyla salisilaldehit, 5-klorosalisilaldehit, 5-bromosalisilaldehit, 5-hidroksisalisilaldehit, 5-metoksisalisilaldehit ve 2-hidroksi-1-naftaldehit ile etanol ortamındaki reaksiyonundan Schiff bazı türü iminopodand bileşikleri (3-8) elde edildi. Bileşik 3' ün etanol ortamında Mn(II), Fe(II), Co(II), Ni(II) ve Cu(II) katyonları ile reaksiyonundan Schiff bazı metal kompleksleri (3a-3e) hazırlandı. Sentezlenen bileşiklerin yapıları FT-IR, UV-VIS., 1H-NMR, 13C-NMR ve TGA spektrumları verilerinden faydalanılarak aydınlatıldı. Ayrıca sentezlenen tüm Schiff bazı iminopodand bileşikleri ile komplekslerinin, mikroorganizmalara karşı antimikrobiyal aktiviteleri incelendi. Anahtar sözcükler: Schif Bazı, Metal Kompleksleri, Spektroskopik Yöntemler, İminopodand, Antimikrobiyal Aktivite.
In this study, nitropodand (1) has been synthesized from the reaction of 1,2-bis-(2-chloroethoxy)ethane and sodium salt of 4-nitrophenol in DMF and by the reduction of this compound aminopodand (2) has been synthesized. Schiff bases type iminopodand compounds (3-8) have been synthesized through the reaction of aminopodand (2) with salicylaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 5-hydroxysalicylal- dehyde, 5-methoxysalicylaldehyde and 2-hydroxy-1-naphtaldehyde in ethanol, respectively. Schiff base metal complexes (3a-3e) have been prepared by the reaction of compound 3 with Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) cations in ethanol, respectively. The structures of synthesized Schiff bases and their complexes were illuminated by means of FT-IR, UV-VIS., 1H-NMR, 13C-NMR, and DTA-TGA data. Moreover, all of the synthesized Schiff bases iminopodand and complexes have been examined in respect of their antimicrobial activities against microorganism. Keywords: Schiff Bases, Metal Complexes, Spectroscopic Methods, Iminopodand, Antimicrobial Activity.
In this study, nitropodand (1) has been synthesized from the reaction of 1,2-bis-(2-chloroethoxy)ethane and sodium salt of 4-nitrophenol in DMF and by the reduction of this compound aminopodand (2) has been synthesized. Schiff bases type iminopodand compounds (3-8) have been synthesized through the reaction of aminopodand (2) with salicylaldehyde, 5-chlorosalicylaldehyde, 5-bromosalicylaldehyde, 5-hydroxysalicylal- dehyde, 5-methoxysalicylaldehyde and 2-hydroxy-1-naphtaldehyde in ethanol, respectively. Schiff base metal complexes (3a-3e) have been prepared by the reaction of compound 3 with Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) cations in ethanol, respectively. The structures of synthesized Schiff bases and their complexes were illuminated by means of FT-IR, UV-VIS., 1H-NMR, 13C-NMR, and DTA-TGA data. Moreover, all of the synthesized Schiff bases iminopodand and complexes have been examined in respect of their antimicrobial activities against microorganism. Keywords: Schiff Bases, Metal Complexes, Spectroscopic Methods, Iminopodand, Antimicrobial Activity.
Açıklama
Fen Bilimleri Enstitüsü, Kimya Ana Bilim Dalı
Anahtar Kelimeler
Kimya, Chemistry
