The advances in functionalized carbon nanomaterials for drug delivery

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dc.authoridSağbaş Suner, Selin / 0000-0002-3524-0675
dc.authoridDemirci, Şahin / 0000-0001-7083-1481
dc.authoridŞahiner, Nurettin / 0000-0003-0120-530X
dc.authoridKurt, Saliha B. / 0000-0003-0346-441X
dc.contributor.authorSağbaş Suner, Selin
dc.contributor.authorKurt, Saliha B.
dc.contributor.authorDemirci, Şahin
dc.contributor.authorŞahiner, Nurettin
dc.date.accessioned2025-01-27T18:53:20Z
dc.date.available2025-01-27T18:53:20Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractCarbon-derived nanostructures, including carbon nanotubes (CNTs), graphene oxide (GO) nanosheets, fullerenes, carbon black (CB) nanomaterials, carbon nanoparticles (CNPs), and carbon dots (CDs), have attracted much attention in a wide range of biomedical areas related to low-toxicity, high bioavailability, low cost, and perfect performances. These carbon-based nanomaterials were generally functionalized by various modification agents such as ionic liquids, amphiphilic polymers, aptamers, biomacromolecules, etc. to improve their utilization and provide advantages in clinical areas. Diagnostics is the most important action to detect and prevent the transmission of disease to others and begin treatment with drug and stem cell therapies. The carbon-derived nanostructures with or without any functionalization can be used for diagnostic purposes as bioimaging and biosensor devices due to their unique optical and electrochemical properties. Nowadays, studies state that functionalized carbon nanomaterials (FCNMs) are promising nano-vehicles for genes, proteins, growth factors, and stem cells, as well as drugs, depending on advanced properties including high mechanical strength and similarity to extracellular networks. Moreover, tunable surface functions of FCNMs provide high loading capacity even for difficult drug molecules, with controllable and long-term release, and targeting ability for a specific site. FCNMs can be used as a theragnostic agent, which is a nanosized agent in therapeutic and diagnostic systems. Stem cells are undifferentiated cells that are usually utilized in theragnostic applications such as tissue engineering and regenerative medicine. FCNMs possess the ability to attach to diverse molecules including the ligands of the cells. This chapter discusses the functionalization and potential use of carbon nanomaterials in diagnosis, drug delivery systems, and stem cell therapy. © 2023 Elsevier Ltd. All rights reserved.
dc.identifier.doi10.1016/B978-0-12-824366-4.00011-X
dc.identifier.endpage241
dc.identifier.isbn978-012824366-4
dc.identifier.isbn978-012824367-1
dc.identifier.scopus2-s2.0-85150092743
dc.identifier.scopusqualityN/A
dc.identifier.startpage197
dc.identifier.urihttps://doi.org/10.1016/B978-0-12-824366-4.00011-X
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12680
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofFunctionalized Carbon Nanomaterials for Theranostic Applications
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectCarbon nanomaterials; Diagnosis; Drug delivery; Functionalization; Stem cell therapy
dc.titleThe advances in functionalized carbon nanomaterials for drug delivery
dc.typeBook Chapter

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