Anesthesia management of a patient with Wilson's disease

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dc.contributor.authorDo?u, Tu?ba
dc.contributor.authorŞahin, Hasan
dc.contributor.authorErbaş, Mesut
dc.contributor.authorŞimşek, Tuncer
dc.contributor.authorToman, Hüseyin
dc.contributor.authorAltinişik, Hatice Betül
dc.contributor.authorKiraz, Hasan Ali
dc.date.accessioned2025-01-27T19:04:17Z
dc.date.available2025-01-27T19:04:17Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractWilson's disease (WD) is an autosomal recessive disorder characterized by mutations in the ATP7B gene, which causes the disorder of copper excretion into bile. In this study we aimed to discuss our anesthesia experience in a Wilson's disease patient who underwent emergency surgical procedures for appendicitis. A 42-year-old male WD patient suffering the disease for 6 years with a diagnosis of cardiomyopathy and asthma, was planned an emergency surgery for appendicitis. The patient's neurological examination was normal. General anesthesia was preffered and for induction 2 mg kg-1 propofol, 1 ?g kg-1 fentanyl, and 0.5 mg kg-1 rocuronium was intravenously administered. Anesthesia was maintained with 50% oxygen and 50% air and 2% sevoflurane. The patient was extubated uneventfully, subsequently postoperative choreiform movements occurred. During the postoperative follow-up, the patient's choreiform movements were observed to disappear and declined by between 3-6 hours. We did not observe a delay in the patient's anesthesia recovery. Consequently, we think general anesthesia can be uneventually applied in Wilson's disease patients by using least toxic agents to the liver, protective measures and with an attentive follow-up in the perioperative and postoperative periods.
dc.identifier.endpage184
dc.identifier.issn1300-0578
dc.identifier.issue3
dc.identifier.scopus2-s2.0-84941614741
dc.identifier.scopusqualityQ4
dc.identifier.startpage182
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13893
dc.identifier.volume23
dc.indekslendigikaynakScopus
dc.language.isotr
dc.publisherAnestezi Dergisi
dc.relation.ispartofAnestezi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectAnesthesia; Wilson disease
dc.titleAnesthesia management of a patient with Wilson's disease
dc.title.alternativeWilson hastali?i olan olguda anestezi yönetimi
dc.typeArticle

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