INTENSIVE PHYSICAL EXERCISE AND KETOSIS IN TYPE 1 DIABETES: LITERATURE REVIEW ON A CASE AFTER COVID-19 QUARANTINE

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dc.contributor.authorCivil, Tamer
dc.contributor.authorOzen, Gokmen
dc.contributor.authorDemirbilek, Huseyin
dc.date.accessioned2025-01-27T20:53:50Z
dc.date.available2025-01-27T20:53:50Z
dc.date.issued2021
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractType 1 diabetes (TD1) is characterized with elevated blood glucose due to insulin deficiency. In case of insulin deficiency glucose can not be used by the body cells to generate energy. Therefore, triglycerides (TG) and free fatty acids ( FFA) become source of energy. Ketone bodies (KBs) are synthesized through beta oxydation of FFAs in the liver. KBs serves as an alternative source of energy. The ability of muscle cells to use KBs in energy production is dependent the insulin. Insulin deficiency in individuals with T1D causes both the increased synthesis of KBs and also inability to use the KBs as source of energy. Accumulation of KBs in the blood is known as hyperketonemia (ketosis). Elevated KBs cause a decrease in blood pH, thereby, a diabetic complication diabetic ketoacidosis develops. On the other hand ketosis in individuals with T1D can develop due to insulin deficiency and prolonged hyperglycemia, as well as prolonged fasting state or prolonged and intensive physical exercises. In this study, we present hyperketonemia situation in a child with T1D that was atributed to the intensive physical exercises in and reviewed the relevant literature data.
dc.identifier.endpage284
dc.identifier.issn2250-0480
dc.identifier.startpage279
dc.identifier.urihttps://hdl.handle.net/20.500.12428/25861
dc.identifier.volume11
dc.identifier.wosWOS:000884778900052
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherInt Journal Lifescience & Pharma Research
dc.relation.ispartofInternational Journal of Life Science and Pharma Research
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectType 1 diabetes
dc.subjectExercise
dc.subjectKetosis
dc.titleINTENSIVE PHYSICAL EXERCISE AND KETOSIS IN TYPE 1 DIABETES: LITERATURE REVIEW ON A CASE AFTER COVID-19 QUARANTINE
dc.typeReview Article

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