EVALUATION OF GENOTOXICITY AND CYTOTOXICITY OF DODINE (1-dodecylguanidium acetate) BY Allium TEST

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dc.authoridKaya, Nergis/0000-0002-4206-1149
dc.contributor.authorCorduk, Nursen
dc.contributor.authorAkinci, Nihan
dc.contributor.authorYucel, Gulru
dc.contributor.authorKaya, Nergis
dc.contributor.authorAkı, Cüneyt
dc.date.accessioned2025-01-27T20:20:20Z
dc.date.available2025-01-27T20:20:20Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractIn this study, we evaluated the genotoxic and cytotoxic effects of dodine, a fungicide extensively used to control scab on apples, pears and pecans, brown rot on peaches and several foliar diseases of cherries, strawberries, peaches and black walnuts. For this purpose the Allium cepa test was carried out exposing roots to dodine for 24, 48 and 72 h at the concentrations of EC50/2, EC50 and 2xEC(50). The mitotic index was calculated as the number of dividing cells per number of 3000-4000 observed cells and the mitotic aberrations also were scored at each concentration. The results showed that dodine induced significant increases of mitotic aberrations such as C-mitosis, polar shifting, laggard chromosome and chromosome fragments. In addition, mitotic index decreased significantly with increasing of concentration and the exposure time as compared to their controls. Hence dodine should be used under control in agricultural fields due to its possible toxic effects.
dc.identifier.endpage4531
dc.identifier.issn1018-4619
dc.identifier.issn1610-2304
dc.identifier.issue12A
dc.identifier.startpage4527
dc.identifier.urihttps://hdl.handle.net/20.500.12428/21669
dc.identifier.volume24
dc.identifier.wosWOS:000367699100020
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherParlar Scientific Publications (P S P)
dc.relation.ispartofFresenius Environmental Bulletin
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectAllium cepa
dc.subjectdodine
dc.subjectcytotoxic
dc.subjectgenotoxic
dc.subjectmitotic aberrations
dc.titleEVALUATION OF GENOTOXICITY AND CYTOTOXICITY OF DODINE (1-dodecylguanidium acetate) BY Allium TEST
dc.typeArticle

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