The relationship between tear osmolarity, ocular surface disease index© and other tear function tests

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dc.contributor.authorTaşkiran Çömez, Arzu
dc.contributor.authorKömür, Bariş
dc.contributor.authorŞanal, Elif
dc.contributor.authorTufan, Hasan Ali
dc.date.accessioned2025-01-27T19:02:26Z
dc.date.available2025-01-27T19:02:26Z
dc.date.issued2013
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: To evaluate the relationship between tear osmolarity, Ocular Surface Disease Index (OSDI© Allergan Inc., Irvine, Calif), Schirmer test and tear break-up time (TBUT). Material and Methods: After performing Ocular Surface Disease Index (OSDI©) survey, tear osmolarity testing with TearLab osmolarity system, Schirmer test without anesthesia and TBUT measurement were performed in 40 patients with dry eye syndrome diagnosis and 39 healthy subjects. Student t-test and Spearman's rho correlation analysis are used for statistical evaluation. Results: The mean tear osmolarity was 307±19.2 mOsm/l in group A, while it was 292.9±13.9 mOsm/l in group B. Schirmer test results were in normal ranges in both groups (13.4±7.5 mm in group A, and 17.4±8.5 mm in group B). TBUT was lower in group A, and the difference between two groups was statistically significant. OSDI© scoring was 43.9±20.4 in group A, while it was 8.56± 5.2 in group B and the difference was statistically significant. The sensitivity and spesificity of tear osmolarity for threshold value 305 mOsm/l were found to be 76.9 % and 80%, for TBUT for 10 seconds were 94.7% and 71.8%; for OSDI© score >15 were 79.5% and 70% and for Schirmer's test for 10 mm were 35.9% and 80%. Conclusion: Of all tests, TBUT, tear osmolarity and OSDI© are found to be successful in discriminating dry eye patients from healthy participants. The specificity and the sensitivity of the commonly used Schirmer test are found to be low. © 2013 by Türkiye Klinikleri.
dc.identifier.doi10.5336/medsci.2012-30139
dc.identifier.endpage463
dc.identifier.issn1300-0292
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84874608628
dc.identifier.scopusqualityQ4
dc.identifier.startpage455
dc.identifier.urihttps://doi.org/10.5336/medsci.2012-30139
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13494
dc.identifier.volume33
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTurkiye Klinikleri
dc.relation.ispartofTurkiye Klinikleri Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectDiagnostic tests; Dry eye syndromes; Osmolar concentration; Routine; Sensitivity and specificity; Tears
dc.titleThe relationship between tear osmolarity, ocular surface disease index© and other tear function tests
dc.title.alternativeGözyaşı osmolaritesinin oküler yüzey hastalık i?ndeksi© ve di?er gözyaşı fonksiyon testleri ile i?lişkisi
dc.typeArticle

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