The role of the tissue culture in granulomatous mediastinal clymphadenitis: Tuberculosis or not

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dc.contributor.authorSevinc, Serpil
dc.contributor.authorOrs Kaya, Seyda
dc.contributor.authorUnsal, Saban
dc.contributor.authorDereli, Sevket
dc.contributor.authorAlar, Timucin
dc.contributor.authorCan Ceylan, Kenan
dc.contributor.authorYucel, Nur
dc.date.accessioned2025-01-27T19:02:47Z
dc.date.available2025-01-27T19:02:47Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim To evaluate the role of the tissue culture via mediastinoscopic biopsy in granulomatous mediastinal lymphadenitis. Methods The dossier data of 92 cases with mediastinal lymphadenitis showing granulomatous lymphadenitis features by cervical mediastinoscopy and whose clinical, radiological and bacteriological definitive diagnosis is tuberculosis and sarcoidosis were examined retrospectively. The rate of the positive tissue culture of mediastynoscopic biopsy in the diagnosis of granulomatous lymphadenitis was calculated. Results There were 65 (71%) females and 27 (29%) males. The mean age of the patients was 42.5 (range 15-75) years. Non necrotizing granulomatous lymphadenitis was detected in 58 (63 %) cases while necrotizing granulomatous lymphadenitis was seen in 34 (37%) cases. There were 29 cases diagnosed with tuberculosis. Acid resistant bacilli culture positive rate was 38% (in 11 cases). There were 21 (62%) cases of necrotizing granulomatous lymphadenitis and eight (14%) cases of non-necrotizing granulomatous lymphadenitis diagnosed with tuberculosis. Culture positivity was identified in two (25%) of eight cases whose differential diagnosis could not be made histopathologically as tuberculosis/sarcoidosis. Conclusions In addition to clinical, radiological and histopathological diagnosis, the study aims to highlight the importance of tissue culture in definitive diagnosis, especially undetermined incidents.
dc.identifier.endpage48
dc.identifier.issn1840-0132
dc.identifier.issue1
dc.identifier.pmid24496340
dc.identifier.scopus2-s2.0-84893328313
dc.identifier.scopusqualityQ2
dc.identifier.startpage44
dc.identifier.urihttps://hdl.handle.net/20.500.12428/13673
dc.identifier.volume11
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherMedical Association of Zenica-Doboj Canton
dc.relation.ispartofMedicinski Glasnik
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20250125
dc.subjectGranulomatous lymphadenitis; Mediastinal lymphadenopathy; Mediastinoscopy; Tissue culture; Tuberculosis
dc.titleThe role of the tissue culture in granulomatous mediastinal clymphadenitis: Tuberculosis or not
dc.typeArticle

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