Evaluation of atherogenic index of plasma levels at hypertensive patients

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dc.contributor.authorYıldırım, Özge Turgay
dc.contributor.authorAkşit, Ercan
dc.contributor.authorAydın, Fatih
dc.contributor.authorAydın, Ayşe Hüseyinoğlu
dc.date.accessioned2025-01-27T19:26:45Z
dc.date.available2025-01-27T19:26:45Z
dc.date.issued2019
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: Hypertension is a major risk factor for cardiovascular system. Recent studies showed that atherogenic index of plasma (AIP) has a strong association with cardiovascular morbidity, all-cause mortality, atherosclerosis and severity of coronary artery disease. It also has a relationship with endothelial damage in hypertensive patients. With this study we aim to investigate the association between AIP and hypertension. Methods: A total of 213 patients were enrolled for the study. Patients with previous hypertension, nephrotic syndrome, diabetes mellitus, hypotiroidism diagnosis, patients under statin treatment and patients under 18 years of age were excluded. Diagnosis of hypertension and blood pressure (BP) results were obtained with 24-hour ambulatory blood pressure monitoring (ABPM). AIP was defined as the logarithmic transformation of the triglyceride to high-density lipoprotein-cholesterol ratio. Results: Mean age of the population was 49.2 ± 14.6 years and 41.8% (n=89) was male. According to 24-hour ABPM results, AIP was positively correlated with day-time systolic blood pressure (SBP) (r=0.244, p<0.001), day-time diastolic blood pressure (DBP) (r=0.276, p<0.001), night-time SBP (r=0.259, p<0.001), night-time DBP (r=0.299, p<0.001), average SBP (r=0.213, p=0.002) and average DBP (r=0.296, p<0.001). AIP was also increased in hypertensive patients compared to normotensive subjects (p=0.001). Conclusion: Results of our study showed that AIP was positively correlated with blood pressure and statistically higher in patients with hypertension.
dc.identifier.doi10.25000/acem.563986
dc.identifier.endpage75
dc.identifier.issn2564-6567
dc.identifier.issue2
dc.identifier.startpage72
dc.identifier.trdizinid319248
dc.identifier.urihttps://doi.org/10.25000/acem.563986
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/319248
dc.identifier.urihttps://hdl.handle.net/20.500.12428/15616
dc.identifier.volume4
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofArchives of Clinical and Experimental Medicine
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_TRD_20250125
dc.subjectGenel ve Dahili Tıp
dc.subjectBiyokimya ve Moleküler Biyoloji
dc.subjectKalp ve Kalp Damar Sistemi
dc.subjectİstatistik ve Olasılık
dc.titleEvaluation of atherogenic index of plasma levels at hypertensive patients
dc.typeArticle

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