Evaluation of Serum Concentration of the Myokine Irisin (FNDC5) in Patients with Age-Related Macular Degeneration

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dc.authorid0000-0002-5393-0557en_US
dc.authorscopusid6701664191en_US
dc.authorwosidK-8932-2014en_US
dc.contributor.authorTurgut, Burak
dc.contributor.authorMercan, Kadir
dc.contributor.authorİlhan, Nevin
dc.contributor.authorAydoğan, Selahattin Semih
dc.date.accessioned2023-04-10T05:56:47Z
dc.date.available2023-04-10T05:56:47Z
dc.date.issued2021en_US
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü
dc.description.abstractObjectives: This study evaluated the serum irisin level of patients with age-related macular degeneration (ARMD) and compared it with that of healthy individuals. Methods: The serum irisin level of 15 healthy controls (Group 1) and 15 dry ARMD patients (Group 2) and 15 wet ARMD patients (Group 3) were measured using the enzyme-linked immunosorbent assay (ELISA) method and compared. Results: There was no statistically significant difference between the groups in terms of age or gender (p>0.05). The mean serum irisin levels of Group 1, Group 2, and Group 3 were 25.81±24.04 ng/mL, 22.93±19.05 ng/mL, and 12.38±8.16 ng/mL, respectively. Although the mean irisin level in the wet ARMD patients was lower than that of the control and dry ARMD groups, there was no statistically significant difference between the groups (p>0.05). Conclusion: The results suggest that the serum irisin level in ARMD patients is not different from that of healthy individuals. Studies of larger groups that examine the irisin level in the vitreous and neovascular membranes will further elucidate any role in the pathogenesis of ARMD.en_US
dc.identifier.citationTurgut, B., Mercan, K., İlhan, N., & Aydoğan, Selahattin Semih. (2021). Evaluation of Serum Concentration of the Myokine Irisin (FNDC5) in Patients with Age-Related Macular Degeneration. Beyoglu Eye Journal, 6(3), 180–184. doi: 10.14744/bej.2021.52533 ‌en_US
dc.identifier.doi10.14744/bej.2021.52533
dc.identifier.endpage184en_US
dc.identifier.issn2459-1777
dc.identifier.issn2587-0394
dc.identifier.issue3en_US
dc.identifier.pmid35005513
dc.identifier.startpage180en_US
dc.identifier.trdizinid476396
dc.identifier.urihttps://beyoglueye.com/jvi.aspx?un=BEJ-52533&volume=6&issue=3
dc.identifier.urihttps://doi.org/10.14744/bej.2021.52533
dc.identifier.urihttps://hdl.handle.net/20.500.12428/3957
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.institutionauthorTurgut, Burak
dc.language.isoen
dc.publisherBeyoglu Eye Training and Research Hospitalen_US
dc.relation.ispartofBeyoglu Eye Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAttribution-NonCommercial-ShareAlike 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/3.0/us/*
dc.subjectAge-related macular degenerationen_US
dc.subjectDryen_US
dc.subjectFNDC5en_US
dc.subjectIrisinen_US
dc.subjectSerum levelen_US
dc.subjectWeten_US
dc.titleEvaluation of Serum Concentration of the Myokine Irisin (FNDC5) in Patients with Age-Related Macular Degeneration
dc.typeArticle

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