The influence of iris color and retina pigment epithelium melanin on allergic rhinitis

dc.authoridKusbeci, Tuncay/0000-0002-5169-4140
dc.contributor.authorDerekoy, Sefa
dc.contributor.authorKenar, Fethullah
dc.contributor.authorYavas, Guliz Fatma
dc.contributor.authorKusbeci, Tuncay
dc.contributor.authorOzturk, Faruk
dc.contributor.authorAycicek, Abdullah
dc.date.accessioned2025-01-27T20:44:13Z
dc.date.available2025-01-27T20:44:13Z
dc.date.issued2016
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: The purpose of this case control study is to establish the influence of iris color and retina pigment epithelium melanin on allergic rhinitis. Methods: Ninety-nine subjects diagnosed prospectively as allergic rhinitis and 85 control subjects were included in the study. Color of iris was recorded after ophthalmic examination. Electro-oculographic measurement was done after pupil dilatation and Arden ratios were recorded. Results: Mean age was 29.44 +/- 9.8 years in subject with allergic rhinitis and 32.67 +/- 12.9 years in control subjects (p>0.05). Measured mean Arden ratio was 158.22 +/- 29.4 in subjects with allergic rhinitis and 179.34 +/- 29.3 in normal subjects (p<0.05). In control group, Arden ratio was significantly higher in eyes with brown iris (p<0.05). In subjects with allergic rhinitis, Arden ratio was significantly lower in brown eyes (p<0.05). Conclusion: An association between allergic rhinitis and melanin content of iris and retina pigment epithelium was found. It can be speculated that pigment-producing system may play a role in the pathogenesis of the allergic rhinitis.
dc.identifier.doi10.2399/jmu.2016001006
dc.identifier.endpage28
dc.identifier.issn2149-7109
dc.identifier.issn2149-6498
dc.identifier.issue1
dc.identifier.startpage23
dc.identifier.urihttps://doi.org/10.2399/jmu.2016001006
dc.identifier.urihttps://hdl.handle.net/20.500.12428/24512
dc.identifier.volume6
dc.identifier.wosWOS:000376231700006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherDeomed Publ, Istanbul
dc.relation.ispartofEnt Updates
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WoS_20250125
dc.subjectAllergic rhinitis
dc.subjectiris color
dc.subjectretina pigment epithelium
dc.subjectArden ratio
dc.subjectmelanin
dc.titleThe influence of iris color and retina pigment epithelium melanin on allergic rhinitis
dc.typeArticle

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