Efficacy of duloxetine in the early management of urinary continence after radical prostatectomy

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dc.contributor.authorAlan, Cabir
dc.contributor.authorEren, Ali E.
dc.contributor.authorErsay, Ahmet R.
dc.contributor.authorKocoglu, Hasan
dc.contributor.authorBasturk, Gokhan
dc.contributor.authorDemirci, Emrah
dc.date.accessioned2025-01-27T18:56:10Z
dc.date.available2025-01-27T18:56:10Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractAim: To evaluate the efficacy of early duloxetine therapy in stress urinary incontinence occurring after radical prostatectomy (RP). Material and Method: Patients that had RP were randomly divided into 2 groups following the removal of the urinary catheter. Group A patients (n = 28) had pelvic floor exercise and duloxetine therapy. Group B patients (n = 30) had only pelvic floor exercise. The incontinence status of the patients and number of pads were recorded and 1-hour pad test and Turkish validation of International Consultation on Incontinence Questionnaire-Short Form test were applied to the patients at the follow-up. Results: When the dry state of the patients was evaluated, 5, 17, 3, and 2 of 28 Group A patients stated that they were completely dry in the 3rd, 6th, 9th and 12th month respectively and pad use was stopped. There was no continence in 30 Group B in the first 3 months. Twelve, 6, and 8 patients stated that they were completely dry in the 6th, 9th and 12th month, respectively. But 3 of 4 patients in whom dryness could not be provided were using a mean of 7.6 pads in the first day and a mean of 1.3 pads after 1 year. When pad use of the patients was evaluated, the mean monthly number of pad use was determined to be 6.2 (4-8) in the initial evaluation, 2.7 (0-5) in the in 3rd month, 2 (0-3) in the 6th month and 1.6 (0-2) pad/d in the 9th month in the group taking medicine. The mean monthly number of pads used was determined to be 5.8 (4-8) in the initial evaluation, 4.3 (3-8) in the 3rd month, 3 (0-6) in the 6th month and 1.6 (0-6) pad/d in the 9th month in the group not taking medicine. Conclusion: According to the results, early duloxetine therapy in stress urinary incontinence that occurred after RP provided early continence. © 2014 S. Karger AG, Basel.
dc.identifier.doi10.1159/000365688
dc.identifier.endpage48
dc.identifier.issn1661-7649
dc.identifier.issue1
dc.identifier.scopus2-s2.0-84929849538
dc.identifier.scopusqualityQ3
dc.identifier.startpage43
dc.identifier.urihttps://doi.org/10.1159/000365688
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12886
dc.identifier.volume8
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherS. Karger AG
dc.relation.ispartofCurrent Urology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectDuloxetine; Radical prostatectomy; Urinary continence
dc.titleEfficacy of duloxetine in the early management of urinary continence after radical prostatectomy
dc.typeArticle

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