The effects of 21 and 23 milimeter aortic valve prosthesis on hemodynamic performance and functional capacity in young adults

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dc.contributor.authorYener, Ali Umit
dc.contributor.authorOzcan, Sedat
dc.contributor.authorBudak, Ali Baran
dc.contributor.authorGenc, Serhat Bahadir
dc.contributor.authorOzkan, Turgut
dc.contributor.authorCicek, Omer Faruk
dc.date.accessioned2025-01-27T18:56:14Z
dc.date.available2025-01-27T18:56:14Z
dc.date.issued2014
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective: Early and medium-term improvement of functional capacity and regression of left ventricular hypertrophy was evaluated in the young adult patient group following application of 21 mm or 23 mm bileaflet aortic mechanical valve prosthesis due to aortic stenosis. Methods: Twenty two patients (10 male, 12 female; mean age 27+-8.2 (19-43)) who underwent isolated aortic valve replacement due to rheumatic aortic stenosis, were included in the study. 21 mm and 23 mm bileaflet mechanical prosthesis was used respectively in eight and fourteen patients. The mean body surface area was 1.86 m2 and 1.68 m2 respectively in 23 mm and 21 mm prosthesis while 1.73 ±0.25 m2 for the whole group. Functional capacity was New York Heart Association (NYHA) class II in 9 patients and class III in thirteen patients. Implantation was performed without enlarging the aortic root in all except four patients. In all patients transvalvular gradients, effective orifice area and the diameter of left ventricle were measured with transthoracic echocardiography during rest and after maximal exercise. Mean followup was 34±12 months (range 11-57 months). Results: There were no postoperative complications or deaths. All the patients were assessed as NYHA class I with regards to functional capacity (p=0.01). Significant improvements were determined in postoperative mean transvalvular gradient (p=0.005) and left ventricular mass index (p=0.01) when compared with preoperative values. Conclusion: Our findings show that replacement with 21 mm and 23 mm mechanical prosthesis provides a significant improvement in regression of symptoms and increase of functional capacity in young adults in early and mid-period without increasing mortality and morbidity.
dc.identifier.doi10.12669/pjms.302.4468
dc.identifier.endpage360
dc.identifier.issn1682-024X
dc.identifier.issue2
dc.identifier.scopus2-s2.0-84896880239
dc.identifier.scopusqualityQ1
dc.identifier.startpage356
dc.identifier.urihttps://doi.org/10.12669/pjms.302.4468
dc.identifier.urihttps://hdl.handle.net/20.500.12428/12911
dc.identifier.volume30
dc.indekslendigikaynakScopus
dc.language.isoen
dc.relation.ispartofPakistan Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_Scopus_20250125
dc.subjectAortic valve; Aortic valve stenosis; Echocardiography; Transvalvular gradient; Valve surgery
dc.titleThe effects of 21 and 23 milimeter aortic valve prosthesis on hemodynamic performance and functional capacity in young adults
dc.typeArticle

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