Chromatographic Applications in Medicine

Chromatography has been preferred in the medical field as one of the most important analytical methods used for the identificationand quantification of a drug and its metabolites in recent years. Various chromatographic techniques have been developed todifferentiate drugs according to their characteristics and interaction types. Among these techniques, particularly High PerformanceAffinity Chromatography (HPAC), Cell Membrane Chromatography (CMC), Mixed Mode Chromatography (MMC), HighPerformance Liquid Chromatography (HPLC) are used for pharmaceutical purposes for bioanalysis of drugs in preclinical and clinicalstudies. The success of Chromatography in the development of rapid and precise analytical methods provides superior specificity andsensitivity in the research of pharmacokinetic properties of drugs in R&D. In personalized medicine, it is important how the dosageand effect of drugs varies from person to person. In recent years, chromotography has been preferred as a promising technique in theanalysis of drug-protein binding and in the examination of clinical or pharmaceutical samples.