Other Mediators At Age-Related Macular Degeneration

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dc.contributor.authorTurgut, Burak
dc.contributor.authorErdogan, Hakika
dc.contributor.authorİlhan, Nevin
dc.contributor.authorErşan, İsmail
dc.date.accessioned2025-05-29T05:42:22Z
dc.date.available2025-05-29T05:42:22Z
dc.date.issued2022
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractObjective Insome patients, even if anti-VEGF therapy is repeatedly administered at certain intervals, no response is obtained. Therefore, a search for new treatment methods has arisen. The aim of this study was to investigate the relevance of mediators such as Erythropoietin, Interleukin 17, and Angiotensin2,which are all involved in proliferation, apoptosis, oxidative stress, and inflammation in age-related macular degeneration. Metods EPO, IL-17, and Angiotensin 2 levels were evaluated by examining the blood samples of patients who did not have any systemic disease or chronic eye disease except Age-related Macular Degeneration (AMD). Results The patients were divided into 3 groups. Groups 1,2, and 3 were determined as the control group, dry type group, and neovascular type group respectively. For the purpose of this study, erythropoietin, interleukin 17, angiotensin2 were examined in the blood samples of patients. As a result of the analyses, a statistically significant difference was detected between the groups in terms of EPO, IL-17, and Angiotensin 2. Conclusion If the relationship between many factors related to age-related macular degeneration can be clearly defined, the perspective on treatment may change, especially in treatment-resistant patients.
dc.identifier.endpage370
dc.identifier.issn2757-847X
dc.identifier.issn2718-0964
dc.identifier.issue3
dc.identifier.startpage365
dc.identifier.urihttps://hdl.handle.net/20.500.12428/32838
dc.identifier.volume3
dc.language.isoen
dc.publisherGaziantep İslam Bilim ve Teknoloji Üniversitesi
dc.relation.ispartofExperimental and Applied Medical Science
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250529
dc.subjectage related macular degeneration
dc.subjecterythropoietin
dc.subjectinterleukin 17
dc.subjectangiotensin 2
dc.titleOther Mediators At Age-Related Macular Degeneration
dc.typeResearch Article

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