Assessment of left atrial functions in cardiac syndrome X

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dc.authoridTENEKECIOGLU, ERHAN/0000-0003-4376-2833
dc.contributor.authorKuzeytemiz, M.
dc.contributor.authorTenekecioglu, E.
dc.contributor.authorYilmaz, M.
dc.contributor.authorSenturk, M.
dc.contributor.authorDemir, S.
dc.contributor.authorBekler, A.
dc.contributor.authorAslan, B.
dc.date.accessioned2025-01-27T20:22:55Z
dc.date.available2025-01-27T20:22:55Z
dc.date.issued2015
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractOBJECTIVE: Cardiac syndrome X (CSX) affects left ventricular functions due to myocardial ischaemia. In this study our aim was to determine the changes in left atrial functions in patients with CSX. PATIENTS AND METHODS: One-hundred patients (M/F; 57/43) diagnosed with CSX in whom ischaemia was detected at exercise test and myocardial perfusion scintigrapghy with normal coronary angiogram and control group of 80 subjects (M/F; 40/40) were recruited into the study. In transthoracic echocardiography and tissue doppler echocardiography, left ventricular and atrial functions were recorded. RESULTS: As compared to control group, left ventricular diastolic functions were impaired (E/A; 0.95 +/- 0.18 vs 1.11 +/- 0.29 p < 0.001), left ventricular end-diastolic pressures were increased (E/Em; 8.1 +/- 1.85 vs 6.9 +/- 1.74 p < 0.05), and left atrial maximum volume, left atrial pre-A volume, left atrial minimum volume were increased in patients with CSX. Left atrial conduit volume was significantly decreased in patients with cardiac syndrome. Left atrial passive emptying volume (LAPEV), left atrial active emptying volume (LAAEV) and left atrial total emptying volume (LATEV) were significantly increased in patients with cardiac syndrome X. Left atrial passive ejection fration (LAPEF) was found similar between the study groups. Left atrial active ejection fraction (LAAEF) was found significantly increased (37.85 +/- 11.89 vs 33.60 +/- 9.21; p = 0.009) in patients with CSX. Left atrial total ejection fraction (LATEF) was increased in the group with cardiac syndrome X but it didn't reach statistical significance (60.85 +/- 8.73 vs 58.36 +/- 8.29; p = 0.054). CONCLUSIONS: Left atrial active contractile pump function increase in response to impaired left ventricular diastolic functions in CSX. Increased left atrial pump function represents a compensatory mechanism in patients with CSX. These results point out the importance of maintaining sinus rythm in patients with CSX.
dc.identifier.endpage3029
dc.identifier.issn1128-3602
dc.identifier.issue16
dc.identifier.pmid26367723
dc.identifier.startpage3023
dc.identifier.urihttps://hdl.handle.net/20.500.12428/22072
dc.identifier.volume19
dc.identifier.wosWOS:000361590800014
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryinfo:eu-repo/semantics/openAccess
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20250125
dc.subjectCoronary artery disease
dc.subjectCardiac syndrome X
dc.subjectLeft atrial function
dc.subjectLeft ventricular Diastolic function
dc.titleAssessment of left atrial functions in cardiac syndrome X
dc.typeArticle

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