Synopsis of Chemical and Drug-Related Agents That Cause Movement Disorders

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dc.contributor.authorKorkmaz, Şükrü Alperen
dc.date.accessioned2026-02-03T11:53:50Z
dc.date.available2026-02-03T11:53:50Z
dc.date.issued2025
dc.departmentÇanakkale Onsekiz Mart Üniversitesi
dc.description.abstractDrug-induced movement disorder (DIMD) is often reversible and secondary to the drugs and substances used. While Parkinsonism is the most common, other movement disorders such as akathisia, tremor, and acute dystonic reactions (ADRs) are also frequently seen due to many agents. DIMDs may be acute and fatal, such as neuroleptic malignant syndrome (NMS) or serotonin syndrome (SS), or maybe seen as tardive syndromes due to long-term exposure. DIMDs exhibit several characteristics that make them easily recognizable, including a well-defined relationship between the start of medication and the emergence of symptoms, a dose-dependent effect, and full recovery upon cessation of the causative substance (except for tardive syndromes). DIMDs are not uncommon and significantly impact on functionality but are often under-recognized or overlooked and not managed appropriately. Identification of risk factors and prevention for DIMDs, if not prevented, early diagnosis and management is a critical consideration in prescribing medications that can cause movement disorders. This chapter focuses on the clinical manifestations, epidemiology, pathophysiology, and treatment of ADRs, acute-subacute akathisia, drug-induced Parkinsonism, drug-induced tremor, tardive syndromes, NMS, and SS. © 2025 Springer Nature Switzerland AG.
dc.identifier.doi10.1007/978-3-031-73368-0_126
dc.identifier.endpage1492
dc.identifier.isbn9783031733673
dc.identifier.isbn9783031733680
dc.identifier.scopus2-s2.0-105023356248
dc.identifier.scopusqualityN/A
dc.identifier.startpage1467
dc.identifier.urihttps://doi.org/10.1007/978-3-031-73368-0_126
dc.identifier.urihttps://hdl.handle.net/20.500.12428/34332
dc.indekslendigikaynakScopus
dc.institutionauthorKorkmaz, Şükrü Alperen
dc.language.isoen
dc.publisherSpringer Science+Business Media
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_Scopus_20260130
dc.subjectAcute dystonic reactions
dc.subjectAkathisia
dc.subjectAntidepressant
dc.subjectAntipsychotic
dc.subjectDrug-induced
dc.subjectDrug-induced movement disorders
dc.subjectDrug-induced Parkinsonism
dc.subjectDrug-induced tremor
dc.subjectExtrapyramidal disorders
dc.subjectExtrapyramidal symptoms
dc.subjectMood-stabilizer
dc.subjectNeuroleptic malignant syndrome
dc.subjectParkinsonism
dc.subjectSerotonin syndrome
dc.subjectTardive dyskinesia
dc.titleSynopsis of Chemical and Drug-Related Agents That Cause Movement Disorders
dc.typeBook Chapter

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